LRRfinder: a web application for the identification of leucine-rich repeats and an integrative Toll-like receptor database

Offord, V; Coffey, T J; Werling, D

doi:10.1016/j.dci.2010.05.004

Adaptive evolution of Toll-like receptor 5 in domesticated mammals
Journal Article
Smith, S. A., Jann, O. C., Haig, D., Russell, G. C., Werling, D., Glass, E. J., & Emes, R. D. Adaptive evolution of Toll-like receptor 5 in domesticated mammals. BMC Evolutionary Biology, 12, Online. https://doi.org/10.1186/1471-2148-12-122

Porcine circovirus type 2 infection before and during an outbreak of postweaning multisystemic wasting syndrome on a pig farm in the UK
Journal Article
Wieland, B., Werling, D., Nevel, M., Grierson, S., Rycroft, A. N., Demmers, T. G. M., …Wathes, C. M. Porcine circovirus type 2 infection before and during an outbreak of postweaning multisystemic wasting syndrome on a pig farm in the UK. Veterinary Record, 170(23), 596+. https://doi.org/10.1136/vr.100276

Assessment and quantification of post-weaning multi-systemic wasting syndrome severity at farm level
Journal Article
Alarcon, P., Velasova, M., Werling, D., Staerk, K. D. C., Chang, Y. M., Nevel, M., …Wieland, B. Assessment and quantification of post-weaning multi-systemic wasting syndrome severity at farm level. Preventive Veterinary Medicine, 98(1), 19-28. https://doi.org/10.1016/j.prevetmed.2010.09.022

TOLL-LIKE RECEPTOR 5 MUTATIONS IN GERMAN SHEPHERD DOGS ARE HYPER-RESPONSIVE TO STIMULATION WITH FLAGELLIN
Journal Article
Allenspach, K., Kathrani, A., House, A. K., Holder, A. L., Catchpole, B., & Werling, D. TOLL-LIKE RECEPTOR 5 MUTATIONS IN GERMAN SHEPHERD DOGS ARE HYPER-RESPONSIVE TO STIMULATION WITH FLAGELLIN. Journal of Veterinary Internal Medicine, 25(3), 688-688

Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines
Journal Article
Burgos, R. A., Conejeros, I., Hidalgo, M. A., Werling, D., & Hermosilla, C. Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines. Veterinary Immunology and Immunopathology, 143(1-2), 1-10. https://doi.org/10.1016/j.vetimm.2011.05.037

Therapeutic targeting of the innate immune system in domestic animals
Journal Article
Coffey, T. J., & Werling, D. Therapeutic targeting of the innate immune system in domestic animals. Cell and Tissue Research, 343(1), 251-261. https://doi.org/10.1007/s00441-010-1054-9

Induction of reactive oxygen species in bovine neutrophils to CD11b, but not dectin-1-dependent
Journal Article
Conejeros, I., Patterson, R., Burgos, R. A., Hermosilla, C., & Werling, D. Induction of reactive oxygen species in bovine neutrophils to CD11b, but not dectin-1-dependent. Veterinary Immunology and Immunopathology, 139(2-4), 308-312. https://doi.org/10.1016/j.vetimm.2010.10.021

Bovine Viral Diarrhea Virus Strain- and Cell Type-Specific Inhibition of Type I Interferon Pathways
Journal Article
Gibson, A. J., Larsson, J., Bateman, M., Brownlie, J., & Werling, D. Bovine Viral Diarrhea Virus Strain- and Cell Type-Specific Inhibition of Type I Interferon Pathways. Journal of Virology, 85(7), 3695-3697. https://doi.org/10.1128/jvi.02626-10

Toll-like receptors in domestic animals
Journal Article
Jungi, T. W., Farhat, K., Burgener, I. A., & Werling, D. Toll-like receptors in domestic animals. Cell and Tissue Research, 343(1), 107-120. https://doi.org/10.1007/s00441-010-1047-8

Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease
Journal Article
Kathrani, A., House, A. K., Catchpole, B., Murphy, A. M., Werling, D., & Allenspach, K. Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease. Tissue Antigens, 78(2), 94-101. https://doi.org/10.1111/j.1399-0039.2011.01707.x

POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS
Journal Article
Kathrani, A., House, A. K., Werling, D., Catchpole, B., Murphy, A. M., & Allenspach, K. POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS. Journal of Veterinary Internal Medicine, 25(3), 696-696

CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease
Journal Article
Kathrani, A., Schmitz, S., Priestnall, S. L., Smith, K. C., Werling, D., Garden, O. A., & Allenspach, K. CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease. Journal of Comparative Pathology, 145(4), 359-366. https://doi.org/10.1016/j.jcpa.2011.03.010

Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK
Journal Article
Kathrani, A., Werling, D., & Allenspach, K. Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK. Veterinary Record, 169(24), E-pub. https://doi.org/10.1136/vr.d5380

MUTATIONAL ANALYSIS OF THE TLR5 GENE IN BOXER DOGS WITH INFLAMMATORY BOWEL DISEASE REVEALS NOVEL POLYMORPHISM IN THE LEUCINE RICH REPEAT DOMAIN
Journal Article
Kathrani, A., Werling, D., & Allenspach, K. MUTATIONAL ANALYSIS OF THE TLR5 GENE IN BOXER DOGS WITH INFLAMMATORY BOWEL DISEASE REVEALS NOVEL POLYMORPHISM IN THE LEUCINE RICH REPEAT DOMAIN. Journal of Veterinary Internal Medicine, 25(3), 696-696

Prevalence of endemic pig diseases in England: an overview six months into a large-scale cross-sectional study on Post-Weaning Multi-systemic Wasting Syndrome (PMWS)
Journal Article
Wieland, B., Alarcon, P., Velasova, M., Nevel, M., Towrie, H., Pfeiffer, D. U., …Werling, D. Prevalence of endemic pig diseases in England: an overview six months into a large-scale cross-sectional study on Post-Weaning Multi-systemic Wasting Syndrome (PMWS)

Molecular cloning and characterization of Toll-like receptors 1-10 in sheep
Journal Article
Chang, J. S., Russell, G. C., Jann, O. C., Glass, E. J., Werling, D., & Haig, D. Molecular cloning and characterization of Toll-like receptors 1-10 in sheep. Veterinary Immunology and Immunopathology, 127(1-2), 94-105. https://doi.org/10.1016/j.vetimm.2008.09.026

Toll-like receptors (TLRs) are pattern-recognition receptors that trigger innate immune responses and stimulate adaptive immunity. Currently, only partial information is available for sheep TLR genes. The aims of this study were to clone and sequence... Read More about Molecular cloning and characterization of Toll-like receptors 1-10 in sheep.

WC1(+)gamma delta T Cells Indirectly Regulate Chemokine Production During Mycobacterium bovis Infection in SCID-bo Mice
Journal Article
Alvarez, A. J., Endsley, J. J., Werling, D., & Estes, D. M. WC1(+)gamma delta T Cells Indirectly Regulate Chemokine Production During Mycobacterium bovis Infection in SCID-bo Mice. Transboundary and Emerging Diseases, 56(6-7), 275-284. https://doi.org/10.1111/j.1865-1682.2009.01081.x

TB or not TB: A Disease Forgotten, but not Gone
Journal Article
Coffey, T. J., & Werling, D. TB or not TB: A Disease Forgotten, but not Gone. Transboundary and Emerging Diseases, 56(6-7), 203-203

The bovine chemokine receptors and their mRNA abundance in mononuclear phagocytes
Journal Article
Widdison, S., Siddiqui, N., Easton, V., Lawrence, F., Ashley, G., Werling, D., …Coffey, T. The bovine chemokine receptors and their mRNA abundance in mononuclear phagocytes. BMC Genomics, 11(439), https://doi.org/10.1186/1471-2164-11-439

LRRfinder: a web application for the identification of leucine-rich repeats and an integrative Toll-like receptor database
Journal Article
Offord, V., Coffey, T. J., & Werling, D. LRRfinder: a web application for the identification of leucine-rich repeats and an integrative Toll-like receptor database. Developmental and Comparative Immunology, 34(10), 1035-1041. https://doi.org/10.1016/j.dci.2010.05.004

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