Skip to main content

Research Repository

Advanced Search

All Outputs (124)

Variation matters: TLR structure and species-specific pathogen recognition
Journal Article
Werling, D., Jann, O. C., Offord, V., Glass, E. J., & Coffey, T. J. Variation matters: TLR structure and species-specific pathogen recognition. Trends in Immunology, 30(3), 124-130. https://doi.org/10.1016/j.it.2008.12.001

Toll-like receptors (TLRs) are a family of pattern recognition receptors that are an important link between innate and adaptive immunity. Many vaccines incorporate ligands for TLRs as an adjuvant and are developed in rodent models, with the resulting... Read More about Variation matters: TLR structure and species-specific pathogen recognition.