Single Nucleotide Polymorphisms in Major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs
(2016)
Journal Article
Peiravan, A., Allenspach, K., Boag, A. M., Soutter, F., Holder, A. L., Catchpole, B., Kennedy, L. J., Werling, D., & Procoli, F. (2016). Single Nucleotide Polymorphisms in Major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs. Veterinary Immunology and Immunopathology, 182, 101-105. https://doi.org/10.1016/j.vetimm.2016.10.012
All Outputs (23)
A Prospective, Randomized, Blinded, Placebo-Controlled Pilot Study on the Effect of Enterococcus faecium on Clinical Activity and Intestinal Gene Expression in Canine Food-Responsive Chronic Enteropathy (2015)
Journal Article
Schmitz, S., Glanemann, B., Garden, O. A., Brooks, H. W., Chang, Y. M., Werling, D., & Allenspach, K. (2015). A Prospective, Randomized, Blinded, Placebo-Controlled Pilot Study on the Effect of Enterococcus faecium on Clinical Activity and Intestinal Gene Expression in Canine Food-Responsive Chronic Enteropathy. Journal of Veterinary Internal Medicine, 29(2), 533-43. https://doi.org/10.1111/jvim.12563
Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease (2014)
Journal Article
Kathrani, A., Lee, H., White, C., Catchpole, B., Murphy, A. M., German, A., Werling, D., & Allenspach, K. (2014). Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease. Veterinary Immunology and Immunopathology, 161(1-2), 32-41. https://doi.org/10.1016/j.vetimm.2014.06.003The most important genetic associations that have been implicated to play a role in the etiology of Crohn's disease (CD) in humans are single nucleotide polymorphisms (SNPs) in nucleotide oligomerisation domain 2 (NOD2). The aim of this study was to... Read More about Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease.
Neutrophil and platelet activation in equine recurrent airway obstruction is associated with increased neutrophil CD13 expression, but not platelet CD41/61 and CD62P or neutrophil-platelet aggregate formation
Journal Article
Dunkel, B., Rickards, K. J., Werling, D., Page, C. P., & Cunningham, F. M. Neutrophil and platelet activation in equine recurrent airway obstruction is associated with increased neutrophil CD13 expression, but not platelet CD41/61 and CD62P or neutrophil-platelet aggregate formation. Veterinary Immunology and Immunopathology, 131(1-2), 25-32. https://doi.org/10.1016/j.vetimm.2009.03.004
Expression of Toll-like receptor 2 in duodenal biopsies from dogs with inflammatory bowel disease is associated with severity of disease
Journal Article
McMahon, L. A., House, A., Catchpole, B., Elson-Riggins, J. G., Riddle, A. L., Smith, K. C., Werling, D., Burgener, I. A., & Allenspach, K. Expression of Toll-like receptor 2 in duodenal biopsies from dogs with inflammatory bowel disease is associated with severity of disease. Veterinary Immunology and Immunopathology, 135(1-2), 158-163. https://doi.org/10.1016/j.vetimm.2009.11.012
Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs.
Journal Article
Kathrani, A., House, A. K., Catchpole, B., Murphy, A., German, A., Werling, D., & Allenspach, K. Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs. PLoS ONE, 5(12), e15740. https://doi.org/10.1371/journal.pone.0015740
Regulation of equine platelet activation by phosphodiesterase (PDE) and the effect of antigen challenge on platelet PDE in horses with recurrent airway obstruction (RAO)
Journal Article
Dunkel, B., Rickards, K. J., Werling, D., Page, C. P., & Cunningham, F. M. Regulation of equine platelet activation by phosphodiesterase (PDE) and the effect of antigen challenge on platelet PDE in horses with recurrent airway obstruction (RAO). American Journal of Veterinary Research, 71(5), 534-540. https://doi.org/10.2460/ajvr.71.5.534
Evaluation of the effect of phosphodiesterase on equine platelet activation and the effect of antigen challenge on platelet phosphodiesterase activity in horses with recurrent airway obstruction
Journal Article
Dunkel, B., Rickards, K. J., Werling, D., Page, C. P., & Cunningham, F. M. Evaluation of the effect of phosphodiesterase on equine platelet activation and the effect of antigen challenge on platelet phosphodiesterase activity in horses with recurrent airway obstruction. American Journal of Veterinary Research, 71(5), 534-540. https://doi.org/10.2460/ajvr.71.5.534
Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies
Journal Article
Allenspach, K., House, A., Smith, K., McNeill, F. M., Hendricks, A., Elson-Riggins, J. G., Riddle, A. L., Steiner, J. M., Werling, D., Garden, O. A., Catchpole, B., & Suchodolski, J. S. Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies. Veterinary Microbiology, 146(3-4), 326-335. https://doi.org/10.1016/j.vetmic.2010.05.025
Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK
Journal Article
Kathrani, A., Werling, D., & Allenspach, K. Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK. Veterinary Record, 169(24), E-pub. https://doi.org/10.1136/vr.d5380
CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease
Journal Article
Kathrani, A., Schmitz, S., Priestnall, S. L., Smith, K. C., Werling, D., Garden, O. A., & Allenspach, K. CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease. Journal of Comparative Pathology, 145(4), 359-366. https://doi.org/10.1016/j.jcpa.2011.03.010
Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease
Journal Article
Kathrani, A., House, A. K., Catchpole, B., Murphy, A. M., Werling, D., & Allenspach, K. Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease. Tissue Antigens, 78(2), 94-101. https://doi.org/10.1111/j.1399-0039.2011.01707.x
Gene expression of selected signature cytokines of T cell subsets in duodenal tissues of dogs with and without inflammatory bowel disease
Journal Article
Schmitz, S., Garden, O. G., Werling, D., & Allenspach, K. Gene expression of selected signature cytokines of T cell subsets in duodenal tissues of dogs with and without inflammatory bowel disease. Veterinary Immunology and Immunopathology, 146(1), 87-91. https://doi.org/10.1016/j.vetimm.2012.01.013
TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin
Journal Article
Kathrani, A., Holder, A. L., Catchpole, B., Alvarez, L., Simpson, K., Werling, D., & Allenspach, K. TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin. PLoS ONE, 7(1), e30117. https://doi.org/10.1371/journal.pone.0030117
Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair
Journal Article
Dakin, S. G., Werling, D., Hibbert, A., Abayasekara, D. R. E., Young, N. J., Smith, R. K. W., & Dudhia, J. Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair. PLoS ONE, 7(2), e32333. https://doi.org/10.1371/journal.pone.0032333
Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease
Journal Article
Dakin, S. G., Dudhia, J., Werling, N. J., Werling, D., Abayasekara, D. R. E., & Smith, R. K. W. Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease. PLoS ONE, 7(11), e48978. https://doi.org/10.1371/journal.pone.0048978
Expression of trefoil factor genes in the duodenum and colon of dogs with inflammatory bowel disease and healthy dogs
Journal Article
Schmitz, S., Hill, S., Werling, D., & Allenspach, K. Expression of trefoil factor genes in the duodenum and colon of dogs with inflammatory bowel disease and healthy dogs. Veterinary Immunology and Immunopathology, 151(1-2), 168-172. https://doi.org/10.1016/j.vetimm.2012.10.009
Comparison of TNF alpha responses induced by Toll-like receptor ligands and probiotic Enterococcus faecium in whole blood and peripheral blood mononuclear cells of healthy dogs
Journal Article
Schmitz, S., Henrich, M., Neiger, R., Werling, D., & Allenspach, K. Comparison of TNF alpha responses induced by Toll-like receptor ligands and probiotic Enterococcus faecium in whole blood and peripheral blood mononuclear cells of healthy dogs. Veterinary Immunology and Immunopathology, 153(1-2), 170-174. https://doi.org/10.1016/j.vetimm.2013.02.014
Stimulation of Duodenal Biopsies and Whole Blood from Dogs with Food-Responsive Chronic Enteropathy and Healthy Dogs with Toll-Like Receptor Ligands and Probiotic Enterococcus faecium
Journal Article
Schmitz, S., Henrich, M., Neiger, R., Werling, D., & Allenspach, K. Stimulation of Duodenal Biopsies and Whole Blood from Dogs with Food-Responsive Chronic Enteropathy and Healthy Dogs with Toll-Like Receptor Ligands and Probiotic Enterococcus faecium. Scandinavian Journal of Immunology, https://doi.org/10.1111/sji.12186
Lack of Correlation between Mucosal Immunoglobulin A-positive Plasma Cell Numbers and TLR5 Genotypes in German Shepherd Dogs with Idiopathic Chronic Enteropathy
Journal Article
Lee, A., Kathrani, A., Priestnall, S. L., Smith, K. C., Werling, D., & Allenspach, K. (in press). Lack of Correlation between Mucosal Immunoglobulin A-positive Plasma Cell Numbers and TLR5 Genotypes in German Shepherd Dogs with Idiopathic Chronic Enteropathy. Journal of Comparative Pathology, 152(2-3), 201-5. https://doi.org/10.1016/j.jcpa.2015.01.002