RESTORING THE READING FRAME IN LARGE DMD DUPLICATION MUTATIONS RESULTS IN DYSTROPHIN EXPRESSION IN VIVO
Journal Article
Muses, S., Jones, H., & Wells, D. J. RESTORING THE READING FRAME IN LARGE DMD DUPLICATION MUTATIONS RESULTS IN DYSTROPHIN EXPRESSION IN VIVO. Neuromuscular Disorders, 22(9-10), 857-857. https://doi.org/10.1016/j.nmd.2012.06.181
All Outputs (89)
Heat shock protein 27 protects against atherogenesis via an Estrogen-Dependent Mechanism: Role of Selective Estrogen Receptor Beta Modulation
Journal Article
Rayner, K., Sun, J., Chen, Y. X., McNulty, M., Simard, T., Zhao, X., …O'Brien, E. R. Heat shock protein 27 protects against atherogenesis via an Estrogen-Dependent Mechanism: Role of Selective Estrogen Receptor Beta Modulation. Arteriosclerosis, Thrombosis, and Vascular Biology, 29(11), 1751-6. https://doi.org/10.1161/ATVBAHA.109.193656
MOVING FORWARD WITH TACT: 2 YEARS ON
Journal Article
Heslop, E., Bushby, K., Csimma, C., Straub, V., & Wells, D. J. MOVING FORWARD WITH TACT: 2 YEARS ON. Neuromuscular Disorders, 22, S33-S33
ARE LARGE-IN-FRAME DUPLICATIONS OF DYSTROPHIN FUNCTIONAL?
Journal Article
Muses, S., Jones, H., & Wells, D. J. ARE LARGE-IN-FRAME DUPLICATIONS OF DYSTROPHIN FUNCTIONAL?. Neuromuscular Disorders, 21(9-10), 713-714. https://doi.org/10.1016/j.nmd.2011.06.997
A New Extensively Characterised Conditionally Immortal Muscle Cell-Line for Investigating Therapeutic Strategies in Muscular Dystrophies
Journal Article
Muses, S., Morgan, J. E., & Wells, D. J. A New Extensively Characterised Conditionally Immortal Muscle Cell-Line for Investigating Therapeutic Strategies in Muscular Dystrophies. PLoS ONE, 6(9), e24826. https://doi.org/10.1371/journal.pone.0024826
Restoration of dystrophin expression using the Sleeping Beauty transposon
Journal Article
Muses, S., Morgan, J. E., & Wells, D. J. Restoration of dystrophin expression using the Sleeping Beauty transposon. https://doi.org/10.1371/currents.RRN1296
Physiological Characterization of muscle strength with variable levels of Dystrophin Restoration in mdx Mice following local antisense therapy
Journal Article
Sharp, P. S., Bye-a-Jee, H., & Wells, D. J. Physiological Characterization of muscle strength with variable levels of Dystrophin Restoration in mdx Mice following local antisense therapy. Molecular Therapy, 19(1), 165-171. https://doi.org/10.1038/mt.2010.213
Forster resonance energy transfer imaging in vivo with approximated radiative transfer equation
Journal Article
Soloviev, V. Y., McGinty, J., Stuckey, D. W., Laine, R., Wylezinska-Arridge, M., Wells, D. J., …Arridge, S. R. Forster resonance energy transfer imaging in vivo with approximated radiative transfer equation. Applied Optics, 50(36), 6583-6590
OUTCOME MEASURES IN THE MDX MOUSE
Journal Article
Wells, D. J. OUTCOME MEASURES IN THE MDX MOUSE. Neuromuscular Disorders, 21, S5-S5
ASSESSING THE THERAPEUTIC POTENTIAL OF LARGE IN A NEW MOUSE MODEL OF DYSTROGLYCANOPATHY
Journal Article
Whitmore, C., Ackroyd, M. R., Muses, S., Ashraf, A., Muntoni, F., Brown, S. C., & Wells, D. J. ASSESSING THE THERAPEUTIC POTENTIAL OF LARGE IN A NEW MOUSE MODEL OF DYSTROGLYCANOPATHY. Neuromuscular Disorders, 21(9-10), 665-665. https://doi.org/10.1016/j.nmd.2011.06.838
Investigation of a transgenic mouse model of familial dilated cardiomyopathy
Journal Article
Song, W., Dyer, E., Stuckey, D., Leung, M., Memo, M., Mansfield, C., …Marston, S. Investigation of a transgenic mouse model of familial dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology, 49(3), 380-389. https://doi.org/10.1016/j.yjmcc.2010.05.009
MDX MICE SHOW CHANGES IN MUSCLE FIBER PROFILE NUMBER WITH AGE
Journal Article
Terry, R. L., Hasan, N., & Wells, D. J. MDX MICE SHOW CHANGES IN MUSCLE FIBER PROFILE NUMBER WITH AGE. Human Gene Therapy, 21(4), 516-516
Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia
Journal Article
Van Der Weerd, L., Tariq Akbar, M., Aron Badin, R., Valentim, L. M., Thomas, D. L., Wells, D. J., …De Belleroche, J. S. Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia. https://doi.org/10.1038/jcbfm.2009.249
Electroporation and ultrasound enhanced non-viral gene delivery in vitro and in vivo
Journal Article
Wells, D. J. Electroporation and ultrasound enhanced non-viral gene delivery in vitro and in vivo. Cell Biology and Toxicology, 26(1), 21-28. https://doi.org/10.1007/s10565-009-9144-8
MAKING SENSE IN DUCHENNE MUSCULAR DYSTROPHY
Journal Article
Wells, D. J. MAKING SENSE IN DUCHENNE MUSCULAR DYSTROPHY. Human Gene Therapy, 21(4), 495-495
Microbubble stability is a major determinant of the efficiency of ultrasound and microbubble mediated in vivo gene transfer
Journal Article
Alter, J., Sennoga, C. A., Lopes, D., Eckserley, R. J., & Wells, D. J. Microbubble stability is a major determinant of the efficiency of ultrasound and microbubble mediated in vivo gene transfer. Ultrasound in Medicine and Biology, 35(6), 976-84. https://doi.org/10.1016/j.ultrasmedbio.2008.12.015
Mice that overexpresses human heat shock protein 27 have increased renal injury following ischemia reperfusion
Journal Article
Chen, S. W. C., Kim, M., Kim, M., Song, J. H., Park, S. W., Wells, D. J., …Lee, H. T. Mice that overexpresses human heat shock protein 27 have increased renal injury following ischemia reperfusion. Kidney International, 75(5), 499-510. https://doi.org/10.1038/ki.2008.572
Heat shock protein 27 overexpression mitigates cytokine-induced islet apoptosis and streptozotocin-induced diabetes
Journal Article
Dai, T., Patel-Chamberlin, M., Natarajan, R., Todorov, I., Ma, J., LaPage, J., …Adler, S. G. Heat shock protein 27 overexpression mitigates cytokine-induced islet apoptosis and streptozotocin-induced diabetes. Endocrinology, 150(7), 3031-9. https://doi.org/10.1210/en.2008-0732
The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development
Journal Article
Heslop, E., Csimma, C., Straub, V., McCall, J., Nagaraju, K., Wagner, K. R., …Wells, D. J. (in press). The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development. Orphanet Journal of Rare Diseases, 10(49), https://doi.org/10.1186/s13023-015-0258-1
Systemic MV Gene Therapy Close to Clinical Trials for Several Neuromuscular Diseases
Journal Article
Wells, D. J. (in press). Systemic MV Gene Therapy Close to Clinical Trials for Several Neuromuscular Diseases. Molecular Therapy, 25(4), 834-835. https://doi.org/10.1016/j.ymthe.2017.03.006