A screen for <i>Plasmodium falciparum</i> sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions
(2024)
Journal Article
Segireddy, R., Belda, H., Yang, A., Dundas, K., Knoeckel, J., Galaway, F., …Douglas, A. (2024). A screen for Plasmodium falciparum sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions. Malaria Journal, 23(1), https://doi.org/10.1186/s12936-024-04913-2
Background Sporozoite invasion of hepatocytes is an essential step in the Plasmodium life-cycle and has similarities, at the cellular level, to merozoite invasion of erythrocytes. In the case of the Plasmodium blood-stage, efforts to identify host-pa... Read More about A screen for <i>Plasmodium falciparum</i> sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions.