All Outputs (2)

Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum (2018)
Journal Article
Soutter, F., Martorell, S., Solano-Gallego, L., & Catchpole, B. (2018). Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum. https://doi.org/10.1016/j.tvjl.2018.03.001

The clinical outcome of Leishmania infantum infection in dogs varies from subclinical infection to severe disease. Researchers attribute this variability in clinical manifestations to the ability of the immune response to limit pathogen multiplicatio... Read More about Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum.

Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185 (2018)
Journal Article
Holder, A. L., Jones, G., Soutter, F., Palmer, D. B., Aspinall, R., & Catchpole, B. (2018). Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185. Developmental and Comparative Immunology, 81, 244-251. https://doi.org/10.1016/j.dci.2017.12.008

Interleukin-7 (IL-7) and its receptor (IL-7R) are essential for T cell development in the thymus, and changes in the IL-7/IL-7R pathway have been implicated in age-associated thymic involution which results in a reduction of naïve T cell output. The... Read More about Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185.