Mitochondria form cholesterol-rich contact sites with the nucleus during retrograde response
(2020)
Journal Article
Desai, R., East, D. A., Hardy, L., Crosby, J., Faccenda, D., Alvarex, M. S., Mainenti, M., Kuhlman Hussy, L., Bentham, R., Szabadkai, G., Zappulli, V., Dhoot, G., Fleck, R. A., Vizcay-Barrena, G., Smith, K., & Campanella, M. (2020). Mitochondria form cholesterol-rich contact sites with the nucleus during retrograde response. Science Advances, https://doi.org/10.1101/445411
Cholesterol metabolism is pivotal to cellular homeostasis, hormones production, and membranes composition. Its dysregulation associates with malignant reprogramming and therapy resistance. Cholesterol is trafficked into the mitochondria for steroidog... Read More about Mitochondria form cholesterol-rich contact sites with the nucleus during retrograde response.