STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression
(2014)
Journal Article
Turnquist, C., Wang, Y., Severson, D. T., Zhong, S., Sun, B., Ma, J., …Lu, X. (2014). STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression. https://doi.org/10.1073/pnas.1407898111
Inflammation and loss of cell polarity play pivotal roles in neurodegeneration and cancer. A central question in both diseases is how the loss of cell polarity is sensed by cell death machinery. Here, we identify apoptosis-stimulating protein of p53... Read More about STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression.