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Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites
Journal Article
Platt, R. N., McDew-White, M., Le Clec'H, W., Chevalier, F. D., Allan, F., Emery, A. M., …Anderson, T. J. C. (in press). Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites. Molecular Biology and Evolution, 36(10), 2127-2142. https://doi.org/10.1093/molbev/msz154

Introgression among parasite species has the potential to transfer traits of biomedical importance across species boundaries. The parasitic blood fluke Schistosoma haematobium causes urogenital schistosomiasis in humans across sub-Saharan Africa. Hyb... Read More about Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites.

Genetic Consequences of Mass Human Chemotherapy for Schistosoma mansoni: Population Structure Pre- and Post-Praziquantel Treatment in Tanzania
Journal Article
Norton, A. J., Gower, C. M., Lamberton, P. H. L., Webster, B. L., Lwambo, N. J. S., Blair, L., …Webster, J. P. Genetic Consequences of Mass Human Chemotherapy for Schistosoma mansoni: Population Structure Pre- and Post-Praziquantel Treatment in Tanzania. American Journal of Tropical Medicine and Hygiene, 83(4), 951-957. https://doi.org/10.4269/ajtmh.2010.10-0283

Analysis of the population genetics of Opisthorchis viverrini sensu lato in the Nam Ngum River wetland, Lao PDR, by multilocus enzyme electrophoresis
Journal Article
Kiatsopit, N., Sithithaworn, P., Saijuntha, W., Pitaksakulrat, O., Petney, T. N., Webster, J. P., & Andrews, R. H. Analysis of the population genetics of Opisthorchis viverrini sensu lato in the Nam Ngum River wetland, Lao PDR, by multilocus enzyme electrophoresis. Parasitology Research, 113(8), 2973-2981. https://doi.org/10.1007/s00436-014-3959-9

Diagnosis and drug resistance of human soil-transmitted helminth infections: A public health perspective
Journal Article
Mutombo, P. N., Man, N. W. Y., Nejsum, P., Ricketson, R., Gordon, C. A., Robertson, G., …McLaws, M. Diagnosis and drug resistance of human soil-transmitted helminth infections: A public health perspective. https://doi.org/10.1016/bs.apar.2019.02.004

Soil-transmitted helminth (STH) infections represent a major public health problem globally, particularly among socio-economically disadvantaged populations. Detection of STH infections is often challenging, requiring a combination of diagnostic tech... Read More about Diagnosis and drug resistance of human soil-transmitted helminth infections: A public health perspective.

Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition
Journal Article
French, M. D., Churcher, T. S., Basáñez, M., Norton, A. J., Lwambo, N. J. S., & Webster, J. P. Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition. Acta Tropica, 128(2), 196-205. https://doi.org/10.1016/j.actatropica.2012.03.001

Detecting potential changes in genetic diversity in schistosome populations following chemotherapy with praziquantel (PZQ) is crucial if we are to fully understand the impact of such chemotherapy with respect to the potential emergence of resistance... Read More about Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition.

Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger
Journal Article
Garba, A., Lamine, M. S., Barkire, N., Djibo, A., Sofo, B., Gouvras, A. N., …Utzinger, J. Efficacy and safety of two closely spaced doses of praziquantel against Schistosoma haematobium and S. mansoni and re-infection patterns in school-aged children in Niger. Acta Tropica, 128(2), 334-344. https://doi.org/10.1016/j.actatropica.2012.08.008

Population genetic structure of Schistosoma mansoni and Schistosoma haematobium from across six sub-Saharan African countries: Implications for epidemiology, evolution and control
Journal Article
Gower, C. M., Gouvras, A. N., Lamberton, P. H. L., Deol, A., Shrivastava, J., Mutombo, P. N., …Webster, J. P. Population genetic structure of Schistosoma mansoni and Schistosoma haematobium from across six sub-Saharan African countries: Implications for epidemiology, evolution and control. Acta Tropica, 128(2), 261-274. https://doi.org/10.1016/j.actatropica.2012.09.014