Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa
(2022)
Journal Article
Papoutsopoulou, S., Tang, J., Elramli, A. H., Williams, J. M., Gupta, N., Ikuomola, F. I., Sheibani-Tezerji, R., Alam, M. T., Hernández-Fernaud, J. R., Caamaño, J. H., Probert, C. S., Muller, W., Duckworth, C. A., & Pritchard, D. M. (2022). Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa. American Journal of Physiology - Gastrointestinal and Liver Physiology, 323(4), G306-G317. https://doi.org/10.1152/ajpgi.00037.2022
Background & aims: The alternative (non-canonical) nuclear factor-kB (NF-kB) signalling pathway predominantly regulates the function of the p52/RelB heterodimer. Germline Nfkb2 deficiency in mice leads to loss of p100/p52 protein and offers protectio... Read More about Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa.