Parkinson’s Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration
(2014)
Journal Article
Tsika, E., Glauser, L., Moser, R., Fiser, A., Daniel, G., Sheerin, U., Lees, A., Troncoso, J. C., Lewis, P. A., Bandopadhyay, R., Schneider, B. L., & Moore, D. J. (2014). Parkinson’s Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration. Human Molecular Genetics, 23(17), 4621-4638. https://doi.org/10.1093/hmg/ddu178
Mutations in the vacuolar protein sorting 35 homolog (VPS35) gene at the PARK17 locus, encoding a key component of the retromer complex, were recently identified as a new cause of late-onset, autosomal dominant Parkinson's disease (PD). Here we explo... Read More about Parkinson’s Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration.