Hyperammonemia and Systemic Inflammatory Response Syndrome Predicts Presence of Hepatic Encephalopathy in Dogs with Congenital Portosystemic Shunts

Tivers, M S; Handel, I; Gow, A G; Lipscomb, V J; Jalan, R; Mellanby, RJ

doi:10.1371/journal.pone.0082303

All Outputs (3)

Hepatic hepcidin gene expression in dogs with a congenital portosystemic shunt (2014)
Journal Article
Frowde, P. E., Gow, A. G., Burton, C. A., Powell, R., Lipscomb, V. J., House, A. K., …Tivers, M. S. (2014). Hepatic hepcidin gene expression in dogs with a congenital portosystemic shunt. Journal of Veterinary Internal Medicine, 28(4), 1203-1205. https://doi.org/10.1111/jvim.12387

Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes (2014)
Journal Article
Thompson, I. R., Mirczuk, S. M., Smith, L., Lessey, A. J., Simbi, B., Sunters, A., …Fowkes, R. C. (2014). Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes. Cell and Tissue Research, 355(2), 425-36. https://doi.org/10.1007/s00441-013-1763-y

The guanylyl cyclases, GC-A and GC-B, are selective receptors for atrial and C-type natriuretic peptides (ANP and CNP, respectively). In the anterior pituitary, CNP and GC-B are major regulators of cGMP production in gonadotropes and yet mouse models... Read More about Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes.

Hyperammonemia and Systemic Inflammatory Response Syndrome Predicts Presence of Hepatic Encephalopathy in Dogs with Congenital Portosystemic Shunts (2014)
Journal Article
Tivers, M. S., Handel, I., Gow, A. G., Lipscomb, V. J., Jalan, R., & Mellanby, R. (2014). Hyperammonemia and Systemic Inflammatory Response Syndrome Predicts Presence of Hepatic Encephalopathy in Dogs with Congenital Portosystemic Shunts. PLoS ONE, 9(1), https://doi.org/10.1371/journal.pone.0082303

Hepatic encephalopathy (HE) is an important cause of morbidity and mortality in patients with liver disease. The pathogenesis of he is incompletely understood although ammonia and inflammatory cytokines have been implicated as key mediators. To facil... Read More about Hyperammonemia and Systemic Inflammatory Response Syndrome Predicts Presence of Hepatic Encephalopathy in Dogs with Congenital Portosystemic Shunts.