Enhanced concentration of COMP (cartilage oligomeric matrix protein) in osteochondral fractures from racing Thoroughbreds
Journal Article
Skioldebrand, E., Heinegard, D., Eloranta, M. L., Nilsson, G., Dudhia, J., Sandgren, B., & Ekinan, S. Enhanced concentration of COMP (cartilage oligomeric matrix protein) in osteochondral fractures from racing Thoroughbreds. Journal of Orthopaedic Research, 23(1), 156-163. https://doi.org/10.1016/j.orthres.2004.05.013
All Outputs (84)
Ultrastructural immunolocalization of cartilage oligomeric matrix protein (COMP) in relation to collagen fibrils in the equine tendon
Journal Article
Sodersten, F., Ekman, S., Eloranta, M. L., Heinegard, D., Dudhia, J., & Hultenby, K. Ultrastructural immunolocalization of cartilage oligomeric matrix protein (COMP) in relation to collagen fibrils in the equine tendon. Matrix Biology, 24(5), 376-385. https://doi.org/10.1016/j.matbio.2005.06.003
Genomics of osteoarthritis
Journal Article
Aigner, T., & Dudhia, J. Genomics of osteoarthritis. Current Opinion in Rheumatology, 15(5), 634-640. https://doi.org/10.1097/00002281-200309000-00019
Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity
Journal Article
Dudhia, J., Scott, C. M., Draper, E. R. C., Heinegard, D., Pitsillides, A. A., & Smith, R. K. W. Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity. Aging Cell, 6(4), 547-556. https://doi.org/10.1111/j.1474-9726.2007.00307.x
Modification of the Composition of Articular Cartilage Collagen Fibrils with Increasing Age
Journal Article
Vaughan-Thomas, A., Dudhia, J., Bayliss, M., Kadler, K., & Duance, V. Modification of the Composition of Articular Cartilage Collagen Fibrils with Increasing Age. Connective Tissue Research, 49(5), 374-382. https://doi.org/10.1080/03008200802325417Recent studies have identified a range of interactions between type IX collagen and other cartilage matrix components. To determine the extent to which these interactions are important in maintaining the integrity of ageing articular cartilage, we an... Read More about Modification of the Composition of Articular Cartilage Collagen Fibrils with Increasing Age.
THE INFLUENCE OF AGEING IN TENDON HOMEOSTASIS AND THE RISK OF TENDON INJURY
Journal Article
Smith, R. K. W., Dudhia, J., Scott, C. M., Draper, E., May, S. A., & Pitsillides, A. A. THE INFLUENCE OF AGEING IN TENDON HOMEOSTASIS AND THE RISK OF TENDON INJURY. International Journal of Experimental Pathology, 89(3), A25-A25
Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor
Journal Article
Dutton, L. C., Dudhia, J., Catchpole, B., Hodhkiss-Geere, H., Werling, D., & Connolly, D. J. (in press). Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor. https://doi.org/10.1038/s41598-018-31569-1derived cells (CDCs) are a cardiac progenitor cell population, which have been shown to possess cardiac regenerative properties and can improve heart function in a variety of cardiac diseases. Studies in large animal models have predominantly focusse... Read More about Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor.
EXPLORING AGE-RELATED CHANGES TO THE PUTATIVE TENDON STEM CELL NICHE
Journal Article
Marr, N., Pitsillides, A. A., Dudhia, J., & Thorpe, C. T. (in press). EXPLORING AGE-RELATED CHANGES TO THE PUTATIVE TENDON STEM CELL NICHE. International Journal of Experimental Pathology, 98(6), A9-A9
Metalloproteinase and tissue inhibitor of metalloproteinase expression in the murine STR/ort model of osteoarthritis
Journal Article
Flannelly, J., Chambers, M. G., Dudhia, J., Hembry, R. M., Murphy, G., Mason, R. M., & Bayliss, M. T. Metalloproteinase and tissue inhibitor of metalloproteinase expression in the murine STR/ort model of osteoarthritis. Osteoarthritis and Cartilage, 10(9), 722-733. https://doi.org/10.1053/joca.2002.0818
MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1
Journal Article
Yamamoto, K., Okano, H., Miyagawa, W., Visse, R., Shitomi, Y., Santamaria, S., …Nagase, H. (in press). MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1. Matrix Biology, 56, 57-73. https://doi.org/10.1016/j.matbio.2016.03.007
Immunophenotypic characterization of ovine mesenchymal stem cells
Journal Article
Khan, M. R., Chandrashekran, A., Smith, R. K. W., & Dudhia, J. (in press). Immunophenotypic characterization of ovine mesenchymal stem cells. Cytometry Part A, 89(5), 443-50. https://doi.org/10.1002/cyto.a.22849
Circulating concentrations of a marker of type I collagen metabolism are associated with hypertrophic cardiomyopathy mutation status in ragdoll cats
Journal Article
Borgeat, K. A., Dudhia, J., Fuentes, V. L., & Connolly, D. J. Circulating concentrations of a marker of type I collagen metabolism are associated with hypertrophic cardiomyopathy mutation status in ragdoll cats. Journal of Small Animal Practice, 56(6), 360-365. https://doi.org/10.1111/jsap.12332
In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy
Journal Article
Dudhia, J., Becerra, P., Valdes, M. A., Neves, F., Hartman, N. G., & Smith, R. K. W. In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy. Journal of Visualized Experiments, https://doi.org/10.3791/52748
INTERLEUKIN-1 ALPHA STIMULATES ADAM17-MEDIATED ECTODOMAIN SHEDDING OF LRP1 AND REDUCES ENDOCYTOSIS OF AGGRECANASES IN ARTICULAR CARTILAGE
Journal Article
Yamamoto, K. Y., Troeberg, L. T., Dudhia, J. D., Murphy, G. M., & Nagase, H. N. INTERLEUKIN-1 ALPHA STIMULATES ADAM17-MEDIATED ECTODOMAIN SHEDDING OF LRP1 AND REDUCES ENDOCYTOSIS OF AGGRECANASES IN ARTICULAR CARTILAGE. International Journal of Experimental Pathology, 96(2), A20-A20
Quantitative proteomics at different depths in human articular cartilage reveals unique patterns of protein distribution
Journal Article
Mueller, C., Khabut, A., Dudhia, J., Reinholt, F. P., Aspberg, A., Heinegard, D., & Onnerfjord, P. (in press). Quantitative proteomics at different depths in human articular cartilage reveals unique patterns of protein distribution. Matrix Biology, 40, 34-45. https://doi.org/10.1016/j.matbio.2014.08.013
Viability of equine mesenchymal stem cells during transport and implantation
Journal Article
Garvican, E. R., Cree, S., Bull, L., Smith, R. K. W., & Dudhia, J. (in press). Viability of equine mesenchymal stem cells during transport and implantation. https://doi.org/10.1186/scrt483
Lentiviral vector transduction of spermatozoa as a tool for the study of early development
Journal Article
Chandrashekran, A., Isa, I., Dudhia, J., Thrasher, A. J., Dibb, N., Casimir, C., …Winston, R. (in press). Lentiviral vector transduction of spermatozoa as a tool for the study of early development. FEBS Open Bio, 4, 266-275. https://doi.org/10.1016/j.fob.2014.02.008Spermatozoa and lentiviruses are two of nature's most efficient gene delivery vehicles. Both can be genetically modified and used independently for the generation of transgenic animals or gene transfer/therapy of inherited disorders. Here we show tha... Read More about Lentiviral vector transduction of spermatozoa as a tool for the study of early development.
Resolving an inflammatory concept: the importance of inflammation and resolution in tendinopathy
Journal Article
Dakin, S. G., Dudhia, J., & Smith, R. K. W. Resolving an inflammatory concept: the importance of inflammation and resolution in tendinopathy. Veterinary Immunology and Immunopathology, 158(3-4), 121-127. https://doi.org/10.1016/j.vetimm.2014.01.007
Mesenchymal stem cells modulate release of matrix proteins from tendon surfaces in vitro: a potential beneficial therapeutic effect
Journal Article
Garvican, E. R., Dudhia, J., Alves, A. L., Clements, L. E., Du Plessis, F., & Smith, R. K. W. Mesenchymal stem cells modulate release of matrix proteins from tendon surfaces in vitro: a potential beneficial therapeutic effect. Regenerative Medicine, 9(3), 295-308. https://doi.org/10.2217/rme.14.7
Distribution of injected technetium(99m)-labeled mesenchymal stem cells in horses with naturally occurring tendinopathy
Journal Article
Becerra, P., Vazquez, M. A. V., Dudhia, J., Fiske-Jackson, A. R., Neves, F., Hartman, N. G., & Smith, R. K. W. Distribution of injected technetium(99m)-labeled mesenchymal stem cells in horses with naturally occurring tendinopathy. Journal of Orthopaedic Research, 31(7), 1096-1102. https://doi.org/10.1002/jor.22338