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All Outputs (3013)

Impact of Facial Conformation on Canine Health: Corneal Ulceration (2015)
Journal Article
Packer, R. M. A., Hendricks, A., & Burn, C. C. (2015). Impact of Facial Conformation on Canine Health: Corneal Ulceration. PLoS ONE, 10(5), e0123827. https://doi.org/10.1371/journal.pone.0123827

Concern has arisen in recent years that selection for extreme facial morphology in the domestic dog may be leading to an increased frequency of eye disorders. Corneal ulcers are a common and painful eye problem in domestic dogs that can lead to scarr... Read More about Impact of Facial Conformation on Canine Health: Corneal Ulceration.

Continuing professional development: learning that leads to change in individual and collective clinical practice (2015)
Journal Article
May, S. A., & Kinnison, T. (2015). Continuing professional development: learning that leads to change in individual and collective clinical practice. Veterinary Record, 177(1), 13-13. https://doi.org/10.1136/vr.103109

The lack of effectiveness of traditional models of continuing professional development is increasingly recognised. While they can lead to increased knowledge of participants, research suggests that there is a general failure to produce meaningful and... Read More about Continuing professional development: learning that leads to change in individual and collective clinical practice.

Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study (2015)
Journal Article
Lee, K. C. L., Baker, L. A., Stanzani, G., Alibhai, H. I. K., Chang, Y. M., Palacios, C. J., …Jalan, R. (2015). Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study. Journal of Hepatology, 63(3), 634-642. https://doi.org/10.1016/j.jhep.2015.04.020

Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme (2015)
Journal Article
Sanchez-Lara, A. C., Elliott, J., Syme, H. M., Brown, C. A., & Haylor, J. L. (2015). Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme. Veterinary Pathology, 52(3), 513-523. https://doi.org/10.1177/0300985814542811

Chronic kidney disease is a major cause of morbidity and mortality in cats. Transglutaminase 2 (TG2) is a calcium-dependent enzyme proposed to mediate tubulointerstitial fibrosis in the kidney by cross-linking collagen fibrils. Postmortem kidney tiss... Read More about Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme.

PinR mediates the generation of reversible population diversity in Streptococcus zooepidemicus (2015)
Journal Article
Steward, K. F., Harrison, T., Robinson, C., Slater, J. D., Maskell, D. J., Harris, S. R., …Waller, A. S. (2015). PinR mediates the generation of reversible population diversity in Streptococcus zooepidemicus. Microbiology, 161, 1105-1112. https://doi.org/10.1099/mic.0.000057

Opportunistic pathogens must adapt to and survive in a wide range of complex ecosystems. Streptococcus zooepidemicus is an opportunistic pathogen of horses and many other animals, including humans. The assembly of different surface architecture pheno... Read More about PinR mediates the generation of reversible population diversity in Streptococcus zooepidemicus.

Prevalence of and risk factors for degenerative mitral valve disease in dogs attending primary-care veterinary practices in england (2015)
Journal Article
Mattin, M. J., Boswood, A., Church, D. B., Lopez-Alvarez, J., McGreevy, P. D., O'Neill, D. G., …Brodbelt, D. C. (2015). Prevalence of and risk factors for degenerative mitral valve disease in dogs attending primary-care veterinary practices in england. Journal of Veterinary Internal Medicine, 29(3), 847-854. https://doi.org/10.1111/jvim.12591

Investigating the Postmortem Molecular Biology of Cartilage and its Potential Forensic Applications (2015)
Journal Article
Bolton, S. N., Whitehead, M. P., Dudhia, J., Baldwin, T. C., & Sutton, R. (2015). Investigating the Postmortem Molecular Biology of Cartilage and its Potential Forensic Applications. Journal of Forensic Sciences, 60(4), 1061-67. https://doi.org/10.1111/1556-4029.12764

This study investigated the postmortem molecular changes that articular cartilage undergoes following burial. Fresh pig trotters were interred in 30‐cm‐deep graves at two distinct locations exhibiting dissimilar soil environments for up to 42 days. E... Read More about Investigating the Postmortem Molecular Biology of Cartilage and its Potential Forensic Applications.

A Prospective, Randomized, Blinded, Placebo-Controlled Pilot Study on the Effect of Enterococcus faecium on Clinical Activity and Intestinal Gene Expression in Canine Food-Responsive Chronic Enteropathy (2015)
Journal Article
Schmitz, S., Glanemann, B., Garden, O. A., Brooks, H. W., Chang, Y. M., Werling, D., & Allenspach, K. (2015). A Prospective, Randomized, Blinded, Placebo-Controlled Pilot Study on the Effect of Enterococcus faecium on Clinical Activity and Intestinal Gene Expression in Canine Food-Responsive Chronic Enteropathy. Journal of Veterinary Internal Medicine, 29(2), 533-43. https://doi.org/10.1111/jvim.12563

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers (2015)
Journal Article
Onegut-Gumuscu, S., Chen, W., Burren, O., Cooper, N. J., Quinlan, A. R., Mychaleckyj, J. C., …Rich, S. S. (2015). Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Nature Genetics, 47(4), 381-6. https://doi.org/10.1038/ng.3245

Genetic studies of type 1 diabetes (T1D) have identified 50 susceptibility regions, finding major pathways contributing to risk, with some loci shared across immune disorders. To make genetic comparisons across autoimmune disorders as informative as... Read More about Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

Susceptibility in vitro of canine methicillin-resistant and -susceptible staphylococcal isolates to fusidic acid, chlorhexidine and miconazole: opportunities for topical therapy of canine superficial pyoderma (2015)
Journal Article
Clark, S. M., Loeffler, A., & Bond, R. (2015). Susceptibility in vitro of canine methicillin-resistant and -susceptible staphylococcal isolates to fusidic acid, chlorhexidine and miconazole: opportunities for topical therapy of canine superficial pyoderma. Journal of Antimicrobial Chemotherapy, 70(7), 2048-52. https://doi.org/10.1093/jac/dkv056