Perturbation of the T cell receptor repertoire occurs with increasing age in dogs
(2018)
Journal Article
Holder, A., Mirczuk, S. M., Fowkes, R. C., Palmer, D. B., Aspinall, R., & Catchpole, B. (2018). Perturbation of the T cell receptor repertoire occurs with increasing age in dogs. Developmental and Comparative Immunology, 79, 150-157. https://doi.org/10.1016/j.dci.2017.10.020
All Outputs (2)
Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185 (2018)
Journal Article
Holder, A. L., Jones, G., Soutter, F., Palmer, D. B., Aspinall, R., & Catchpole, B. (2018). Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185. Developmental and Comparative Immunology, 81, 244-251. https://doi.org/10.1016/j.dci.2017.12.008Interleukin-7 (IL-7) and its receptor (IL-7R) are essential for T cell development in the thymus, and changes in the IL-7/IL-7R pathway have been implicated in age-associated thymic involution which results in a reduction of naïve T cell output. The... Read More about Polymorphisms in the canine IL7R 3 ' UTR are associated with thymic output in Labrador retriever dogs and influence post-transcriptional regulation by microRNA 185.