All Outputs (13)

Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease (2014)
Journal Article
Kathrani, A., Lee, H., White, C., Catchpole, B., Murphy, A. M., German, A., …Allenspach, K. (2014). Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease. Veterinary Immunology and Immunopathology, 161(1-2), 32-41. https://doi.org/10.1016/j.vetimm.2014.06.003

The most important genetic associations that have been implicated to play a role in the etiology of Crohn's disease (CD) in humans are single nucleotide polymorphisms (SNPs) in nucleotide oligomerisation domain 2 (NOD2). The aim of this study was to... Read More about Association between nucleotide oligomerisation domain two(Nod2) gene polymorphisms and canine inflammatory bowel disease.

Lack of Correlation between Mucosal Immunoglobulin A-positive Plasma Cell Numbers and TLR5 Genotypes in German Shepherd Dogs with Idiopathic Chronic Enteropathy
Journal Article
Lee, A., Kathrani, A., Priestnall, S. L., Smith, K. C., Werling, D., & Allenspach, K. (in press). Lack of Correlation between Mucosal Immunoglobulin A-positive Plasma Cell Numbers and TLR5 Genotypes in German Shepherd Dogs with Idiopathic Chronic Enteropathy. Journal of Comparative Pathology, 152(2-3), 201-5. https://doi.org/10.1016/j.jcpa.2015.01.002

TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin
Journal Article
Kathrani, A., Holder, A. L., Catchpole, B., Alvarez, L., Simpson, K., Werling, D., & Allenspach, K. TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin. PLoS ONE, 7(1), e30117. https://doi.org/10.1371/journal.pone.0030117

TOLL-LIKE RECEPTOR 5 MUTATIONS IN GERMAN SHEPHERD DOGS ARE HYPER-RESPONSIVE TO STIMULATION WITH FLAGELLIN
Journal Article
Allenspach, K., Kathrani, A., House, A. K., Holder, A. L., Catchpole, B., & Werling, D. TOLL-LIKE RECEPTOR 5 MUTATIONS IN GERMAN SHEPHERD DOGS ARE HYPER-RESPONSIVE TO STIMULATION WITH FLAGELLIN. Journal of Veterinary Internal Medicine, 25(3), 688-688

Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease
Journal Article
Kathrani, A., House, A. K., Catchpole, B., Murphy, A. M., Werling, D., & Allenspach, K. Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease. Tissue Antigens, 78(2), 94-101. https://doi.org/10.1111/j.1399-0039.2011.01707.x

POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS
Journal Article
Kathrani, A., House, A. K., Werling, D., Catchpole, B., Murphy, A. M., & Allenspach, K. POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS. Journal of Veterinary Internal Medicine, 25(3), 696-696

CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease
Journal Article
Kathrani, A., Schmitz, S., Priestnall, S. L., Smith, K. C., Werling, D., Garden, O. A., & Allenspach, K. CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease. Journal of Comparative Pathology, 145(4), 359-366. https://doi.org/10.1016/j.jcpa.2011.03.010

Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK
Journal Article
Kathrani, A., Werling, D., & Allenspach, K. Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK. Veterinary Record, 169(24), E-pub. https://doi.org/10.1136/vr.d5380

MUTATIONAL ANALYSIS OF THE TLR5 GENE IN BOXER DOGS WITH INFLAMMATORY BOWEL DISEASE REVEALS NOVEL POLYMORPHISM IN THE LEUCINE RICH REPEAT DOMAIN
Journal Article
Kathrani, A., Werling, D., & Allenspach, K. MUTATIONAL ANALYSIS OF THE TLR5 GENE IN BOXER DOGS WITH INFLAMMATORY BOWEL DISEASE REVEALS NOVEL POLYMORPHISM IN THE LEUCINE RICH REPEAT DOMAIN. Journal of Veterinary Internal Medicine, 25(3), 696-696

POLYMORPHISMS IN TOLL-LIKE RECEPTOR 5 RESULT IN HYPER-RESPONSIVENESS TO FLAGELLIN
Journal Article
Kathrani, A., Werling, D., Holder, A. L., Catchpole, B., & Allenspach, K. POLYMORPHISMS IN TOLL-LIKE RECEPTOR 5 RESULT IN HYPER-RESPONSIVENESS TO FLAGELLIN. Journal of Veterinary Internal Medicine, 25(3), 687-688

Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs.
Journal Article
Kathrani, A., House, A. K., Catchpole, B., Murphy, A., German, A., Werling, D., & Allenspach, K. Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs. PLoS ONE, 5(12), e15740. https://doi.org/10.1371/journal.pone.0015740

OVERDOMINANT SINGLE NUCLEOTIDE POLYMORPHISMS IN THE NUCLEOTIDE OLIGOMERISATION DOMAIN TWO (NOD2) GENE ARE SIGNIFICANTLY ASSOCIATED WITH CANINE INFLAMMATORY BOWEL DISEASE
Journal Article
Kathrani, A., House, A. K., Werling, D., Catchpole, B., Murphy, A., German, A. J., …Allenspach, K. OVERDOMINANT SINGLE NUCLEOTIDE POLYMORPHISMS IN THE NUCLEOTIDE OLIGOMERISATION DOMAIN TWO (NOD2) GENE ARE SIGNIFICANTLY ASSOCIATED WITH CANINE INFLAMMATORY BOWEL DISEASE. Journal of Veterinary Internal Medicine, 24(3), 176

CD11c POSITIVE DENDRITIC CELLS ARE SIGNIFICANTLY DECREASED IN THE DUODENUM OF DOGS WITH INFLAMMATORY BOWEL DISEASE
Journal Article
Kathrani, A., House, A., Werling, D., Smith, K. C., Garden, O. A., Simbi, B. H., & Allenspach, K. CD11c POSITIVE DENDRITIC CELLS ARE SIGNIFICANTLY DECREASED IN THE DUODENUM OF DOGS WITH INFLAMMATORY BOWEL DISEASE. Journal of Veterinary Internal Medicine, 24(3), 175