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All Outputs (191)

English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections (2022)
Journal Article
O’Neill, D. G., Skipper, A., Packer, R. M. A., Lacey, C., Church, D. B., Brodbelt, D. C., & Pegram, C. (2022). English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections. Canine Medicine and Genetics, 9(1), https://doi.org/10.1186/s40575-022-00118-5

Background The English Bulldog has risen sharply in popularity over the past decade but its distinctive and extreme conformation is linked to several serious health conditions. Using multivariable analysis of anonymised veterinary clinical data from... Read More about English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections.

Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom (2022)
Journal Article
Tzu-yun Teng, K., Brodbelt, D., Pegram, C., Church, D., & O’Neill, D. (2022). Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom. Scientific Reports, 12(1), 6415. https://doi.org/10.1038/s41598-022-10341-6

A life table is a tabulated expression of life expectancy and mortality-related information at specified ages in a given population. This study applied the VetCompass Programme to generate life tables for the UK dog population both overall and broken... Read More about Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom.

Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016 (2022)
Journal Article
Beeston, D., Humm, K., Church, D. B., Brodbelt, D., & O'Neill, D. G. (in press). Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16389

Background: Urethral obstruction (UO) has a negative effect on welfare of cats. Objectives: This study aimed to determine incidence, case management, and outcomes of UO in cats in primary-care practice in the United Kingdom. Animals: All male c... Read More about Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016.

Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study (2022)
Journal Article
O'Neill, D., Yahui, Y., Roser, T. P., Dave C., B., David B., C., Camilla, P., & Minn, M. (2022). Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study. (Con)textos Linguísticos, 17(1), https://doi.org/10.1371/journal.pone.0260538

Background Prolapsed nictitating membrane gland (PNMG) is the most common disorder of the third eyelid in dogs. However, the epidemiology of PNMG in the wider dog population remains understudied. Methods Using de-identified clinical data from th... Read More about Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study.

Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care (2022)
Journal Article
Pegram, C., Craven, A., Packer, R., Jarvis, S., McGreevy, P., Warnes, C., …O'Neill, D. (in press). Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care. PLoS ONE, 17, https://doi.org/10.1371/journal.pone.0261139

Undesirable behaviours (UBs) in dogs are common and important issues with serious potential welfare consequences for both the dogs and their owners. This study aimed to investigate the usage of drug therapy for UBs in dogs and assess demographic risk... Read More about Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care.

Incidence and demographic risk factors for leptospirosis in dogs in the UK (2021)
Journal Article
Taylor, C., O'Neill, D. G., Catchpole, B., & Brodbelt, D. C. (in press). Incidence and demographic risk factors for leptospirosis in dogs in the UK. Veterinary Record, https://doi.org/10.1002/vetr.512

Objectives To estimate the annual incidence risk of leptospirosis diagnosis in practice-attending dogs in the UK during 2016 and identify risk factors for diagnosis. Methods Incidence of leptospirosis diagnosis in dogs during 2016 was estima... Read More about Incidence and demographic risk factors for leptospirosis in dogs in the UK.

Machine-learning based prediction of Cushing’s syndrome in dogs attending UK primary-care veterinary practice (2021)
Journal Article
Schofield, I., Brodbelt, D. C., Kennedy, N., Niessen, S. J. M., Church, D. B., Geddes, R. F., & O’Neill, D. G. (2021). Machine-learning based prediction of Cushing’s syndrome in dogs attending UK primary-care veterinary practice. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-88440-z

Cushing’s syndrome is an endocrine disease in dogs that negatively impacts upon the quality-of-life of affected animals. Cushing’s syndrome can be a challenging diagnosis to confirm, therefore new methods to aid diagnosis are warranted. Four machine-... Read More about Machine-learning based prediction of Cushing’s syndrome in dogs attending UK primary-care veterinary practice.

Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK (2021)
Journal Article
Pegram, C., Raffan, E., White, E., Ashworth, A., Brodbelt, D., Church, D., & O'Neill, D. (2021). Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13325

Objectives: To evaluate the prevalence and risk factors for overweight status in dogs under primary veterinary care in the UK. Methods: A retrospective study design was used to estimate the one-year (2016) period prevalence of overweight status. The... Read More about Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK.

Spatio-temporal distribution and agroecological factors associated with canine leptospirosis in Great Britain (2021)
Journal Article
Taylor, C., Brodbelt, D. C., Dobson, B. A., Catchpole, B., O'neill, D. G., & Stevens, K. B. (2021). Spatio-temporal distribution and agroecological factors associated with canine leptospirosis in Great Britain. Preventive Veterinary Medicine, 193, https://doi.org/10.1016/j.prevetmed.2021.105407

Leptospirosis is an important global zoonotic disease that affects a wide range of mammalian species. Canine leptospirosis outbreaks have been reported after flooding (eg. in Brazil and the United States of America) suggesting an environmental associ... Read More about Spatio-temporal distribution and agroecological factors associated with canine leptospirosis in Great Britain.

Hypoadrenocorticism in dogs under UK primary veterinary care: frequency, clinical approaches and risk factors (2020)
Journal Article
Schofield, I., Woolhead, V., Johnson, A., Brodbelt, D. C., Church, D. B., & O'Neill, D. G. (2020). Hypoadrenocorticism in dogs under UK primary veterinary care: frequency, clinical approaches and risk factors. Journal of Small Animal Practice, 1-8. https://doi.org/10.1111/jsap.13285

Objectives: To estimate the frequency, clinical approaches and risk factors of hypoadrenocorticism in dogs under UK primary veterinary care. Materials and MethOds: Dogs diagnosed with hypoadrenocorticism were identified from the UK VetCompass™ progr... Read More about Hypoadrenocorticism in dogs under UK primary veterinary care: frequency, clinical approaches and risk factors.

Side Effects to Systemic Glucocorticoid Therapy in Dogs Under Primary Veterinary Care in the UK (2020)
Journal Article
Elkholly, D., Brodbelt, D., Church, D., Pelligand, L., Mwacalimba, K., Wright, A., & O'Neill, D. (2020). Side Effects to Systemic Glucocorticoid Therapy in Dogs Under Primary Veterinary Care in the UK. Frontiers in Veterinary Science, 7,

Objectives: Systemic glucocorticoids are widely used in companion animals. This study aimed to estimate the frequency, describe the characteristics and to evaluate risk factors for common side effects to systemic glucocorticoid therapy in dogs under... Read More about Side Effects to Systemic Glucocorticoid Therapy in Dogs Under Primary Veterinary Care in the UK.

Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management (2020)
Journal Article
Radulescu, S. M., Humm, K., Eramanis, L. M., Volk, H. A., Church, D. B., Brodbelt, D., & O'Neill, D. G. (2020). Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15869

Background Vestibular disease (VD), central or peripheral, can be a dramatic primary‐care presentation. Current literature describes mostly dogs examined in referral centers. Hypothesis/Objectives Describe the prevalence, presentation, clini... Read More about Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management.

Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management (2020)
Journal Article
Radulescu, S. M., Humm, K., Eramanis, L. M., Volk, H. A., Church, D. B., Brodbelt, D., & O'Neill, D. G. (2020). Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management. Journal of Veterinary Internal Medicine, 34(5), 1993-2004. https://doi.org/10.1111/jvim.15869

Background Vestibular disease (VD), central or peripheral, can be a dramatic primary‐care presentation. Current literature describes mostly dogs examined in referral centers. Hypothesis/Objectives Describe the prevalence, presentation, clini... Read More about Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management.

Clinical management of lipomas in dogs under primary care in the UK (2020)
Journal Article
Pegram, C. L., Rutherford, L., Corah, C., Church, D. B., Brodbelt, D. C., & O'Neill, D. G. (2020). Clinical management of lipomas in dogs under primary care in the UK. Veterinary Record, vetrec-2019

Lipomas are relatively common and biologically benign masses of mesenchymal origin consisting of adipocytes. This study reports benchmark data on the clinical management and outcomes of lipomas in dogs under UK primary veterinary care. The study used... Read More about Clinical management of lipomas in dogs under primary care in the UK.

Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival (2020)
Journal Article
Heeley, A., O’Neill, D., Davison, L., Church, D., Corless, E., & Brodbelt, D. (2020). Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival. Canine Medicine and Genetics, 7(1), https://doi.org/10.1186/s40575-020-00087-7

Background: Diabetes mellitus (DM) is an important endocrine disorder of dogs. The objectives of this study were to estimate prevalence and incidence of DM in dogs, and to explore risk factors for DM and the survival of DM cases in primary-care clini... Read More about Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival.