Endotoxin-induced activation of equine platelets: evidence for direct activation of p38 MAPK pathways and vasoactive mediator production

Brooks, A C; Menzies-Gow, N J; Wheeler-Jones, C P D; Bailey, S R; Cunningham, F M; Elliott, J

doi:10.1007/s00011-006-6151-6

Endocrinopathic Laminitis: Reducing the Risk Through Diet and Exercise
Journal Article
Menzies-Gow, N. J. Endocrinopathic Laminitis: Reducing the Risk Through Diet and Exercise. https://doi.org/10.1016/j.cveq.2010.04.005

Epidemiological study of pasture-associated laminitis and concurrent risk factors in the South of England
Journal Article
Menzies-Gow, N. J., Katz, L. M., Barker, K. J., Elliott, J., De Brauwere, M. N., Jarvis, N., Marr, C. M., & Pfeiffer, D. U. Epidemiological study of pasture-associated laminitis and concurrent risk factors in the South of England. Veterinary Record, 167(18), 690-694. https://doi.org/10.1136/vr.c5177

Severity and outcome of equine pasture-associated laminitis managed in first opinion practice in the UK
Journal Article
Menzies-Gow, N. J., Stevens, K. B., Barr, A. R. S., Camm, I., Pfeiffer, D. U., & Marr, C. M. Severity and outcome of equine pasture-associated laminitis managed in first opinion practice in the UK. Veterinary Record, 167(10), 364-369. https://doi.org/10.1136/vr.c3206

Repeatability and reproducibility of the Obel grading system for equine laminitis
Journal Article
Menzies-Gow, N. J., Stevens, K. B., Sepulveda, M. F., Jarvis, N., & Marr, C. M. Repeatability and reproducibility of the Obel grading system for equine laminitis. Veterinary Record, 167(2), 52-55. https://doi.org/10.1136/vr.c3668

Endotoxin-induced activation of equine digital vein endothelial cells: Role of p38 MAPK
Journal Article
Brooks, A. C., Menzies-Gow, N. J., Wheeler-Jones, C. P. D., Bailey, S. R., Cunningham, F. M., & Elliott, J. Endotoxin-induced activation of equine digital vein endothelial cells: Role of p38 MAPK. Veterinary Immunology and Immunopathology, 129(3-4), 174-180. https://doi.org/10.1016/j.vetimm.2008.11.008

Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases
Journal Article
Brooks, A. C., Menzies-Gow, N. J., Wheeler-Jones, C. P. D., Bailey, S. R., Elliott, J., & Cunningham, F. M. Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases. Journal of Veterinary Pharmacology and Therapeutics, 32(2), 189-196. https://doi.org/10.1111/j.1365-2885.2008.01020.x

Lipopolysaccharide (LPS) can activate equine platelets directly or indirectly, via leukocyte-derived platelet activating factor (PAF). Thromboxane (Tx) production by LPS-stimulated equine platelets requires p38 MAPK and this kinase has been suggested... Read More about Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases.

Diabetes in the horse: A condition of increasing clinical awareness for differential diagnosis and interpretation of tests
Journal Article
Menzies-Gow, N. J. Diabetes in the horse: A condition of increasing clinical awareness for differential diagnosis and interpretation of tests. Equine Veterinary Journal, 41(9), 841-843. https://doi.org/10.2746/042516409x471412

ECG interpretation in the horse
Journal Article
Menzies-Gow, N. J. ECG interpretation in the horse. In Practice, 23(8), 454+

Equine electrocardiography: Techniques and interpretation
Journal Article
Menzies-Gow, N. J. Equine electrocardiography: Techniques and interpretation

Coronary band dystrophy in two horses
Journal Article
Menzies-Gow, N. J., Bond, R., Patterson-Kane, J. C., & McGowan, C. M. Coronary band dystrophy in two horses. Veterinary Record, 150(21), 665-668

Chronic nodular panniculitis in a three-year-old mare
Journal Article
Menzies-Gow, N. J., Patterson-Kane, J. C., & McGowan, C. M. Chronic nodular panniculitis in a three-year-old mare. Veterinary Record, 151(14), 416+

Hypertension and insulin resistance in a mixed-breed population of ponies predisposed to laminitis
Journal Article
Bailey, S. R., Habershon-Butcher, J. L., Ransom, K. J., Elliott, J., & Menzies-Gow, N. J. Hypertension and insulin resistance in a mixed-breed population of ponies predisposed to laminitis. American Journal of Veterinary Research, 69(1), 122-129. https://doi.org/10.2460/ajvr.69.1.122

Objective - To determine the metabolic phenotype of a group of laminitis-prone ponies when at pasture in summer, compared with when at pasture in winter. Animals - 40 ponies of various breeds predisposed to recurrent pasture-associated laminitis and... Read More about Hypertension and insulin resistance in a mixed-breed population of ponies predisposed to laminitis.

Evaluation of the induction of vasoactive mediators from equine digital vein endothelial cells by endotoxin
Journal Article
Menzies-Gow, N. J., Bailey, S. R., Berhane, Y., Brooks, A. C., & Elliott, J. Evaluation of the induction of vasoactive mediators from equine digital vein endothelial cells by endotoxin. American Journal of Veterinary Research, 69(3), 349-355

Objective - To determine the effect of endotoxin (lipopolysaccharide [LPS]) on vasoactive mediator production by cultured equine digital vein endothelial cells (EDVECs). Sample Population - EDVECs obtained from forelimb digital veins of 7 healthy adu... Read More about Evaluation of the induction of vasoactive mediators from equine digital vein endothelial cells by endotoxin.

Four cases of equine polysaccharide storage myopathy in the United Kingdom
Journal Article
McGowan, C. M., Menzies-Gow, N. J., McDiarmid, A. M., & Patterson-Kane, J. C. Four cases of equine polysaccharide storage myopathy in the United Kingdom. Veterinary Record, 152(4), 109-112

Use of nuclear scintigraphy with Tc-99m-HMPAO-labelled leucocytes to assess small intestinal malabsorption in 17 horses
Journal Article
Menzies-Gow, N. J., Weller, R., Bowen, I. M., Corley, K. T. T., Livesey, L., Weaver, M., & Marr, C. M. Use of nuclear scintigraphy with Tc-99m-HMPAO-labelled leucocytes to assess small intestinal malabsorption in 17 horses. Veterinary Record, 153(15), 457+

Digital blood flow and plasma endothelin concentration in clinically endotoxemic horses
Journal Article
Menzies-Gow, N. J., Bailey, S. R., Stevens, K. B., Katz, L., Elliott, J., & Marr, C. M. Digital blood flow and plasma endothelin concentration in clinically endotoxemic horses. American Journal of Veterinary Research, 66(4), 630-636. https://doi.org/10.2460/ajvr.2005.66.630

The effects of vasoactive amines found in the equine hindgut on digital blood flow in the normal horse
Journal Article
Bailey, S. R., Menzies-Gow, N. J., Marr, C. M., & Elliott, J. The effects of vasoactive amines found in the equine hindgut on digital blood flow in the normal horse. Equine Veterinary Journal, 36(3), 267-272

Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators
Journal Article
Menzies-Gow, N. J., Bailey, S. R., Katz, L. M., Marr, C. M., & Elliott, J. Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. Equine Veterinary Journal, 36(3), 273-278. https://doi.org/10.2746/0425164044877260

Repeatability of Doppler ultrasonographic measurement of equine digital blood flow
Journal Article
Menzies-Gow, N. J., & Marr, C. M. Repeatability of Doppler ultrasonographic measurement of equine digital blood flow. https://doi.org/10.1111/j.1740-8261.2007.00243.x

Endotoxin-induced activation of equine platelets: evidence for direct activation of p38 MAPK pathways and vasoactive mediator production
Journal Article
Brooks, A. C., Menzies-Gow, N. J., Wheeler-Jones, C. P. D., Bailey, S. R., Cunningham, F. M., & Elliott, J. Endotoxin-induced activation of equine platelets: evidence for direct activation of p38 MAPK pathways and vasoactive mediator production. Inflammation Research, 56(4), 154-161. https://doi.org/10.1007/s00011-006-6151-6

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