Parkinson’s Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration
(2014)
Journal Article
Tsika, E., Glauser, L., Moser, R., Fiser, A., Daniel, G., Sheerin, U., …Moore, D. J. (2014). Parkinson’s Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration. Human Molecular Genetics, 23(17), 4621-4638. https://doi.org/10.1093/hmg/ddu178
Mutations in the vacuolar protein sorting 35 homolog (VPS35) gene at the PARK17 locus, encoding a key component of the retromer complex, were recently identified as a new cause of late-onset, autosomal dominant Parkinson's disease (PD). Here we explo... Read More about Parkinson’s Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration.