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Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming (2016)
Journal Article
Easton, A. V., Oliveira, R. G., O'Connell, E. M., Kepha, S., Mwandawiro, C. S., Njenga, S. M., …Nutman, T. B. (2016). Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming. https://doi.org/10.1186/s13071-016-1314-y

Recovery of chronically lame dairy cows following treatment for claw horn lesions: a randomised controlled trial (2016)
Journal Article
Thomas, H. J., Remnant, J. G., Bollard, N. J., Burrows, A., Whay, H. R., Bell, N. J., …Huxley, J. N. (2016). Recovery of chronically lame dairy cows following treatment for claw horn lesions: a randomised controlled trial. Veterinary Record, 178(5), 116-U54. https://doi.org/10.1136/vr.103394

A positively controlled, randomised controlled trial (RCT) was undertaken to test recovery of cows with claw horn lesions resulting in lameness of greater than two weeks duration. Cows on seven commercial farms were mobility scored fortnightly and se... Read More about Recovery of chronically lame dairy cows following treatment for claw horn lesions: a randomised controlled trial.

Interaction of the tetracyclines with double-stranded RNAs of random base sequence: new perspectives on the target and mechanism of action (2016)
Journal Article
Chukwudi, C. U., & Good, L. (2016). Interaction of the tetracyclines with double-stranded RNAs of random base sequence: new perspectives on the target and mechanism of action. Journal of Antibiotics, 69, 622-630. https://doi.org/10.1038/ja.2015.145

The 16S rRNA binding mechanism proposed for the antibacterial action of the tetracyclines does not explain their mechanism of action against non-bacterial pathogens. In addition, several contradictory base pairs have been proposed as their binding si... Read More about Interaction of the tetracyclines with double-stranded RNAs of random base sequence: new perspectives on the target and mechanism of action.

Exploring the evidence base for national and regional policy interventions to combat resistance (2016)
Journal Article
Dar, F. K., Littmann, J., Rweyemamu, M., Buckley, E. J., Shahid, M., Kock, R. A., …Heymann, D. L. (2016). Exploring the evidence base for national and regional policy interventions to combat resistance. https://doi.org/10.1016/S0140-6736%2815%2900520-6

The effectiveness of existing policies to control antimicrobial resistance is not yet fully understood. A strengthened evidence base is needed to inform effective policy interventions across countries with different income levels and the human health... Read More about Exploring the evidence base for national and regional policy interventions to combat resistance.

Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons (2016)
Journal Article
Thorpe, C. T., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2016). Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons. Acta Biomaterialia, 42, 308-315. https://doi.org/10.1016/j.actbio.2016.06.012

Tendon is composed of rope-like fascicles, bound together by interfascicular matrix (IFM). Our previous work shows that the IFM is critical for tendon function, facilitating sliding between fascicles to allow tendons to stretch. This function is part... Read More about Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons.

Diagnosis of tuberculosis in groups of badgers: an exploration of the impact of trapping efficiency, infection prevalence and the use of multiple tests (2016)
Journal Article
Buzdugan, S. N., Chambers, M. A., Delahay, R. J., & Drewe, J. A. (2016). Diagnosis of tuberculosis in groups of badgers: an exploration of the impact of trapping efficiency, infection prevalence and the use of multiple tests. Epidemiology and Infection, 144(8), 1717-1727. https://doi.org/10.1017/S0950268815003210

Accurate detection of infection with Mycobacterium bovis in live badgers would enable targeted tuberculosis control. Practical challenges in sampling wild badger populations mean that diagnosis of infection at the group (rather than the individual) l... Read More about Diagnosis of tuberculosis in groups of badgers: an exploration of the impact of trapping efficiency, infection prevalence and the use of multiple tests.