All Outputs (2)

Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease) (2016)
Journal Article
Wager, K., Zdebik, A. A., Fu, S., Cooper, J. D., Harvey, R. J., & Russell, C. (2016). Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease). PLoS ONE, 11(6), https://doi.org/10.1371/journal.pone.0157365

The neuronal ceroid lipofuscinoses are a group of lysosomal storage disorders that comprise the most common, genetically heterogeneous, fatal neurodegenerative disorders of children. They are characterised by childhood onset, visual failure, epilepti... Read More about Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease).

Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1 (2016)
Journal Article
Matic, I., Cocco, S., Ferraina, C., Martin-Jimenez, R., Florenzano, F., Crosby, J., …Campanella, M. (2016). Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1. Pharmacological Research, 103(1), 56-68. https://doi.org/10.1016/j.phrs.2015.10.010

The mitochondrial ATPase Inhibitory Factor 1 (hereafter referred to as IF1) blocks the reversal of the F1Fo-ATPsynthase to prevent detrimental consumption of cellular ATP and associated demise. Herein, we infer further its molecular physiology by ass... Read More about Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1.