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Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats (2016)
Journal Article
Pelligand, L., Soubret, A., King, J. N., Elliott, J., & Mochel, J. P. (2016). Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats. https://doi.org/10.1002/psp4.12141

The objective of this study was to model the pharmacokinetics (PKs) of robenacoxib in cats using a nonlinear mixed‐effects (NLME) approach, leveraging all available information collected from cats receiving robenacoxib s.c. and/or i.v.: 47 densely sa... Read More about Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats.

Factors influencing the relationship between the dose of amlodipine required for blood pressure control and change in blood pressure in hypertensive cats (2016)
Journal Article
Bijsmans, E. S., Doig, M., Jepson, R. E., Syme, H. M., Elliott, J., & Pelligand, L. (2016). Factors influencing the relationship between the dose of amlodipine required for blood pressure control and change in blood pressure in hypertensive cats. Journal of Veterinary Internal Medicine, 30(5), 1630-1636. https://doi.org/10.1111/jvim.14562

Use of the oral sugar test in ponies when performed with or without prior fasting (2016)
Journal Article
Knowles, E. J., Harris, P. A., Elliott, J., & Menzies-Gow, N. J. (2016). Use of the oral sugar test in ponies when performed with or without prior fasting. Equine Veterinary Journal, 49, 519-524. https://doi.org/10.1111/evj.12607

Background It is recommended that the Oral Sugar Test (OST) for insulin dysregulation (ID) is performed after an overnight fast but fasting is impractical in ponies kept solely at pasture. There are few data on OST repeatability and reliability in p... Read More about Use of the oral sugar test in ponies when performed with or without prior fasting.

Chronic kidney disease in aged cats: Clinical features, morphology, and proposed pathogeneses (2016)
Journal Article
Brown, C., Elliott, J., Schmiedt, C., & Brown, S. (2016). Chronic kidney disease in aged cats: Clinical features, morphology, and proposed pathogeneses. Veterinary Pathology, 53(2), 309-326. https://doi.org/10.1177/0300985815622975

Chronic kidney disease (CKD) is the most common metabolic disease of domesticated cats, with most affected cats being geriatric (>12 years of age). The prevalence of CKD in cats exceeds that observed in dogs, and the frequency of the diagnosis of CKD... Read More about Chronic kidney disease in aged cats: Clinical features, morphology, and proposed pathogeneses.

Urinary active transforming growth factor ß in feline chronic kidney disease (2016)
Journal Article
Lawson, J. S., Syme, H. M., Wheeler-Jones, C. P. D., & Elliott, J. (2016). Urinary active transforming growth factor ß in feline chronic kidney disease. https://doi.org/10.1016/j.tvjl.2016.02.004

The cytokine transforming growth factor beta 1 (TGF-β1) has been widely implicated in the development and progression of renal fibrosis in chronic kidney disease (CKD) in humans and in experimental models. The aims of this study were to assess the as... Read More about Urinary active transforming growth factor ß in feline chronic kidney disease.