All Outputs (6)

A compendium and functional characterization of mammalian genes involved in adaptation to Arctic or Antarctic environments (2017)
Journal Article
Yudin, N. S., Larkin, D. M., & Ignatieva, E. V. (2017). A compendium and functional characterization of mammalian genes involved in adaptation to Arctic or Antarctic environments. BMC Genetics, 18, https://doi.org/10.1186/s12863-017-0580-9

Many mammals are well adapted to surviving in extremely cold environments. These species have likely accumulated genetic changes that help them efficiently cope with low temperatures. It is not known whether the same genes related to cold adaptation... Read More about A compendium and functional characterization of mammalian genes involved in adaptation to Arctic or Antarctic environments.

Genome-wide genotyping uncovers genetic profiles and history of the Russian cattle breeds (2017)
Journal Article
Yurchenko, A., Yudin, N., Aitnazarov, R., Plyusnina, A., Brukhin, V., Soloshenko, V., …Larkin, D. M. (2017). Genome-wide genotyping uncovers genetic profiles and history of the Russian cattle breeds. Heredity, 120(2), 125-137. https://doi.org/10.1038/s41437-017-0024-3

One of the most economically important areas within the Russian agricultural sector is dairy and beef cattle farming contributing about $11 billion to the Russian economy annually. Trade connections, selection and breeding have resulted in the establ... Read More about Genome-wide genotyping uncovers genetic profiles and history of the Russian cattle breeds.

X Chromosome Evolution in Cetartiodactyla (2017)
Journal Article
Proskuryakova, A. A., Kulemzina, A. I., Perelman, P. L., Makunin, I. A., Larkin, D. M., Farré, M., …Graphodatsky, S. A. (2017). X Chromosome Evolution in Cetartiodactyla. Genes, 8(9), 216. https://doi.org/10.3390/genes8090216

The phenomenon of a remarkable conservation of the X chromosome in eutherian mammals has been first described by Susumu Ohno in 1964. A notable exception is the cetartiodactyl X chromosome, which varies widely in morphology and G-banding pattern betw... Read More about X Chromosome Evolution in Cetartiodactyla.

Reconstruction and evolutionary history of eutherian chromosomes (2017)
Journal Article
Kim, J., Farre Belmonte, M., Auvil, L. S., Capitanu, B., Larkin, D. M., Ma, J., & Lewin, H. A. (2017). Reconstruction and evolutionary history of eutherian chromosomes. Proceedings of the National Academy of Sciences, 114(27), E5379-E5388. https://doi.org/10.1073/pnas.1702012114

Whole-genome assemblies of 19 placental mammals and two outgroup species were used to reconstruct the order and orientation of syntenic fragments in chromosomes of the eutherian ancestor and six other descendant ancestors leading to human. For ancest... Read More about Reconstruction and evolutionary history of eutherian chromosomes.

Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set (2017)
Journal Article
Damas, J., O'Connor, R., Farré, M., Lenis, V. P. E., Martell, H. J., Mandawala, A., …Larkin, D. M. (2017). Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set. Genome Research, 27, 697-708. https://doi.org/10.1101/gr.213660.116

Most recent initiatives to sequence and assemble new species’ genomes de novo fail to achieve the ultimate endpoint to produce contigs, each representing one whole chromosome. Even the best-assembled genomes (using contemporary technologies) consist... Read More about Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set.

The genomes and history of domestic animals (2017)
Journal Article
Larkin, D. M., & Yudin, N. S. (2017). The genomes and history of domestic animals. Molecular Genetics, Microbiology and Virology, 31(4), 197-202. https://doi.org/10.3103/S0891416816040054

This paper reviews how mammalian genomes are utilized in modern genetics for the detection of genes and polymorphisms (mutations) within domesticated animal (mostly livestock) genomes that are related to traits of economic importance to humans. Examp... Read More about The genomes and history of domestic animals.