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All Outputs (9)

Patterns of microchromosome organization remain highly conserved throughout avian evolution (2018)
Journal Article
O'Connor, R. E., Kiazim, L., Skinner, B., Fonseka, G., Joseph, S., Jennings, R., & Larkin, D. M. (2018). Patterns of microchromosome organization remain highly conserved throughout avian evolution. Chromosoma, 128(1), 21-29. https://doi.org/10.1007/s00412-018-0685-6

The structure and organization of a species genome at a karyotypic level, and in interphase nuclei, have broad functional significance. Although regular sized chromosomes are studied extensively in this regard, microchromosomes, which are present in... Read More about Patterns of microchromosome organization remain highly conserved throughout avian evolution.

Chromosome Level Genome Assembly and Comparative Genomics between Three Falcon Species Reveals an Unusual Pattern of Genome Organisation (2018)
Journal Article
Joseph, S., O'Connor, R. E., Al Mutery, A., Watson, M., Larkin, D. M., & Griffin, D. (2018). Chromosome Level Genome Assembly and Comparative Genomics between Three Falcon Species Reveals an Unusual Pattern of Genome Organisation. Diversity, 10(4), 113. https://doi.org/10.3390/d10040113

Whole genome assemblies are crucial for understanding a wide range of aspects of falcon biology, including morphology, ecology, and physiology, and are thus essential for their care and conservation. A key aspect of the genome of any species is its k... Read More about Chromosome Level Genome Assembly and Comparative Genomics between Three Falcon Species Reveals an Unusual Pattern of Genome Organisation.

Scans for signatures of selection in Russian cattle breed genomes reveal new candidate genes for environmental adaptation and acclimation (2018)
Journal Article
Yurchenko, A. A., Daetwyler, H. D., Yudin, N., Schnabel, R. D., Vander Jagt, C. J., Soloshenko, V., …Larkin, D. M. (2018). Scans for signatures of selection in Russian cattle breed genomes reveal new candidate genes for environmental adaptation and acclimation. https://doi.org/10.1038/s41598-018-31304-w

Domestication and selective breeding has resulted in over 1000 extant cattle breeds. Many of these breeds do not excel in important traits but are adapted to local environments. These adaptations are a valuable source of genetic material for efforts... Read More about Scans for signatures of selection in Russian cattle breed genomes reveal new candidate genes for environmental adaptation and acclimation.

Construction of Red Fox Chromosomal Fragments from the Short-Read Genome Assembly (2018)
Journal Article
Rando, H., Farré, M., Robson, M., Won, N., Johnson, J., Buch, R., …Kukekova, A. (2018). Construction of Red Fox Chromosomal Fragments from the Short-Read Genome Assembly. Genes, 9(6), 308. https://doi.org/10.3390/genes9060308

The genome of a red fox (Vulpes vulpes) was recently sequenced and assembled using next-generation sequencing (NGS). The assembly is of high quality, with 94X coverage and a scaffold N50 of 11.8 Mbp, but is split into 676,878 scaffolds, some of which... Read More about Construction of Red Fox Chromosomal Fragments from the Short-Read Genome Assembly.

Reconstruction of the diapsid ancestral genome permits chromosome evolution tracing in avian and non-avian dinosaurs (2018)
Journal Article
O'Connor, R. E., Romanov, M. N., Kiazim, L. G., Barrett, P. M., Farre Belmonte, M., Damas, J., …Griffin, D. K. (2018). Reconstruction of the diapsid ancestral genome permits chromosome evolution tracing in avian and non-avian dinosaurs. Nature Communications, 9(1), 1883. https://doi.org/10.1038/s41467-018-04267-9

Genomic organisation of extinct lineages can be inferred from extant chromosome-level genome assemblies. Here, we apply bioinformatic and molecular cytogenetic approaches to determine the genomic structure of the diapsid common ancestor. We then infe... Read More about Reconstruction of the diapsid ancestral genome permits chromosome evolution tracing in avian and non-avian dinosaurs.

Chromosome Segregation Is Biased by Kinetochore Size (2018)
Journal Article
Drpic, D., Almeida, A. C., Aguiar, P., Renda, F., Damas, J., Lewin, H. A., …Maiato, H. (2018). Chromosome Segregation Is Biased by Kinetochore Size. Current Biology, 28(9), 1344-1365. https://doi.org/10.1016/j.cub.2018.03.023

Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selectio... Read More about Chromosome Segregation Is Biased by Kinetochore Size.

Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD (2018)
Journal Article
Perelman, P. L., Pichler, R., Gaggl, A., Larkin, D. M., Raudsepp, T., Alshanbari, F., …Periasamy, K. (2018). Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD. Scientific Reports, 8(1), https://doi.org/10.1038/s41598-018-20223-5

The availability of genomic resources including linkage information for camelids has been very limited. Here, we describe the construction of a set of two radiation hybrid (RH) panels (5000RAD and 15000RAD) for the dromedary (Camelus dromedarius) as... Read More about Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD.