Skip to main content

Research Repository

Advanced Search

All Outputs (4)

Imaging of focal seizures with Electrical Impedance Tomography and depth electrodes in real time (2021)
Journal Article
Witkowska-Wrobel, A., Aristovich, K., Crawford, A., Perkins, J., & Holder, D. (2021). Imaging of focal seizures with Electrical Impedance Tomography and depth electrodes in real time. NeuroImage, 234, https://doi.org/10.1016/j.neuroimage.2021.117972

A B S T R A C T Intracranial EEG is the current gold standard technique for localizing seizures for surgery, but it can be insen-sitive to tangential dipole or distant sources. Electrical Impedance Tomography (EIT) offers a novel method to improve co... Read More about Imaging of focal seizures with Electrical Impedance Tomography and depth electrodes in real time.

Human-relevant near-organ neuromodulation of the immune via the nerve (2021)
Journal Article
Donega, M., Fjordbakk, C., Kirk, J., Sokal, D., Gupta, I., Hunsberger, G., …Perkins, J. (2021). Human-relevant near-organ neuromodulation of the immune via the nerve. Proceedings of the National Academy of Sciences, 118(20), https://doi.org/10.1073/pnas.2025428118

Neuromodulation of immune function by stimulating the autonomic connections to the spleen has been demonstrated in rodent models. Consequently, neuroimmune modulation has been proposed as a new therapeutic strategy for the treatment of inflammatory c... Read More about Human-relevant near-organ neuromodulation of the immune via the nerve.

Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation (2021)
Journal Article
Aristovich, K., Donega, M., Fjordbakk, C., Tarotin, I., Chapman, C., Viscasillas, J., …Holder, D. (2021). Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation. Journal of Neuroscience Methods, 352, https://doi.org/10.1016/j.jneumeth.2021.109079

Background: Neuromodulation by electrical stimulation of the human cervical vagus nerve may be limited by adverse side effects due to stimulation of off-target organs. It may be possible to overcome this by spatially selective stimulation of peripher... Read More about Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation.

Neurological Examination In Healthy Juvenile Bearded Dragons (Pogona Vitticeps) And Adult Leopard Geckos (Eublepharis Macularius) (2021)
Journal Article
Hedley, J., MacHale, J., Rendle, M., & Crawford, A. (2021). Neurological Examination In Healthy Juvenile Bearded Dragons (Pogona Vitticeps) And Adult Leopard Geckos (Eublepharis Macularius). Journal of Herpetological Medicine and Surgery, https://doi.org/10.5818/JHMS-D-20-00006

A variety of neurological disorders have been reported in reptiles, but evaluation of a reptile patient with suspected neurological disease can be challenging. The feasibility of performing and interpreting neurological examinations may be affected b... Read More about Neurological Examination In Healthy Juvenile Bearded Dragons (Pogona Vitticeps) And Adult Leopard Geckos (Eublepharis Macularius).