All Outputs (3)

Bone marrow lesions: plugging the holes in our knowledge using animal models (2023)
Journal Article
Hansen, R., Chenu, C., Sofat, N., & Pitsillides, A. (2023). Bone marrow lesions: plugging the holes in our knowledge using animal models. Nature Reviews Rheumatology, https://doi.org/10.1038/s41584-023-00971-z

Bone marrow lesions (BMLs), which are early signs of osteoarthritis (OA) that are associated with the presence, onset and severity of pain, represent an emerging imaging biomarker and clinical target. Little is known, however, regarding their early s... Read More about Bone marrow lesions: plugging the holes in our knowledge using animal models.

Regional modular responses in different bone compartments to the anabolic effect of PTH (1-34) and axial loading in mice (2023)
Journal Article
Monzem, S., Valkani, D., Evans, L., Chang, Y., & Pitsillides, A. (2023). Regional modular responses in different bone compartments to the anabolic effect of PTH (1-34) and axial loading in mice. BONE, 170, https://doi.org/10.1016/j.bone.2023.116720

Beneficial effects of intermittent parathyroid hormone (PTH) on bone mass and architecture are described to either simply add to, or to synergise with those of mechanical loading. We evaluate whether interaction with in vivo loading is reinforced by... Read More about Regional modular responses in different bone compartments to the anabolic effect of PTH (1-34) and axial loading in mice.

The tendon interfascicular basement membrane provides a vascular niche for CD146+ cell subpopulations (2023)
Journal Article
Marr, N., Zamboulis, D. E., Werling, D., Felder, A. A., Dudhia, J., Pitsillides, A. A., & Thorpe, C. T. (2023). The tendon interfascicular basement membrane provides a vascular niche for CD146+ cell subpopulations. Frontiers in Cell and Developmental Biology, 10, https://doi.org/10.3389/fcell.2022.1094124