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Welcome to RVC Repository

RVC Research Online is a repository of the research outputs produced by staff from the Royal Veterinary College (RVC). The aims of the repository are (i) to provide an institutional archive of RVC's research outputs, (ii) to provide access to these outputs and support open science, and (iii) to increase the reach and impact of RVC's research.

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Latest Additions

Time kill curve PD modelling experiments are affected by trailing MIC endpoints: refinement of MIC determination for S. pseudintermedius (2025)
Journal Article
Mead, A., & Pelligand, L. (2025). Time kill curve PD modelling experiments are affected by trailing MIC endpoints: refinement of MIC determination for S. pseudintermedius. Journal of Veterinary Pharmacology and Therapeutics. https://doi.org/10.1111/jvp.70033

Trailing endpoints are a recognised challenge in broth microdilution MIC testing, particularly for bacteriostatic agents such as trimethoprim (TMP) and sulphonamides. In this study, we applied a pharmacodynamically guided refinement to determine the... Read More about Time kill curve PD modelling experiments are affected by trailing MIC endpoints: refinement of MIC determination for S. pseudintermedius.

Clinical Value of Various Histological Factors in Cutaneous and Subcutaneous Mast Cell Tumors in 197 Dogs (2025)
Journal Article
O'Neill, D., Boyd, K., Dobromylskyj, M., Davies, O., Schofield, I., & Figueroa, C. (2025). Clinical Value of Various Histological Factors in Cutaneous and Subcutaneous Mast Cell Tumors in 197 Dogs. Herpetological Conservation and Biology, 39(6), e70244. https://doi.org/10.1111/jvim.70244

Background: Many histological tests have been correlated with outcome in mast cell tumors (MCTs)in dogs, but their statistical
independence is uncertain.
Objective: To investigate the clinical value of histological factors in the prognostication of... Read More about Clinical Value of Various Histological Factors in Cutaneous and Subcutaneous Mast Cell Tumors in 197 Dogs.

Incidence and risk factors for phaeochromocytoma diagnosis in dogs under primary veterinary care in the UK (2025)
Journal Article
Litviakov, M., O'Neill, D. G., Brodbelt, D. C., Galac, S., & Buishand, F. O. (2025). Incidence and risk factors for phaeochromocytoma diagnosis in dogs under primary veterinary care in the UK. PLoS ONE. https://doi.org/10.1371/journal.pone.0332811

Phaeochromocytoma (PCC) is a tumour arising from the adrenal gland in dogs that can be challenging to diagnose. This study aimed to describe the incidence risk, breed predispositions and other demographic risk factors associated with the diagnosis PC... Read More about Incidence and risk factors for phaeochromocytoma diagnosis in dogs under primary veterinary care in the UK.