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The broiler meat system in Nairobi, Kenya: using a value chain framework to understand animal and product flows, governance and sanitary risks (2017)
Journal Article
Carron, M., Alarcon, P., Karani, M., Muinde, P., Akoko, J., Onono, J., …Rushton, J. (2017). The broiler meat system in Nairobi, Kenya: using a value chain framework to understand animal and product flows, governance and sanitary risks. Preventive Veterinary Medicine, 147, 90-99. https://doi.org/10.1016/j.prevetmed.2017.08.013

Livestock food systems play key subsistence and income generation roles in low to middle income countries and are important networks for zoonotic disease transmission. The aim of this study was to use a value chain framework to characterize the broil... Read More about The broiler meat system in Nairobi, Kenya: using a value chain framework to understand animal and product flows, governance and sanitary risks.

Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis (2017)
Journal Article
Kamaruzzaman, N. F., Chong, S. Q. Y., Edmondson-Brown, K. M., Ntow-Boahene, W., Bardiau, M., & Good, L. (2017). Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis. Frontiers in Microbiology, 11(8), 1518. https://doi.org/10.3389/fmicb.2017.01518

Staphylococcus aureus infection is a common cause of mastitis, reducing milk yield, affecting animal welfare and causing huge economic losses within the dairy industry. In addition to the problem of acquired drug resistance, bacterial invasion into u... Read More about Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis.

A Systematic Review and Meta-Analysis of Practices Exposing Humans to Avian Influenza Viruses, Their Prevalence, and Rationale (2017)
Journal Article
Fournié, G., Høg, E., Barnett, T., Pfeiffer, D. U., & Mangtani, P. (2017). A Systematic Review and Meta-Analysis of Practices Exposing Humans to Avian Influenza Viruses, Their Prevalence, and Rationale. American Journal of Tropical Medicine and Hygiene, 97(2), 376-388. https://doi.org/10.4269/ajtmh.17-0014

Almost all human infections by avian influenza viruses (AIVs) are transmitted from poultry. A systematic review was conducted to identify practices associated with human infections, their prevalence, and rationale. Observational studies were identifi... Read More about A Systematic Review and Meta-Analysis of Practices Exposing Humans to Avian Influenza Viruses, Their Prevalence, and Rationale.

Cultural Practices Shaping Zoonotic Diseases Surveillance: The Case of Highly Pathogenic Avian Influenza and Thailand Native Chicken Farmers (2017)
Journal Article
Delabouglise, A., Antoine-Moussiaux, N., Tatong, D., Chumkaeo, A., Binot, A., Fournié, G., …Peyre, M. (2017). Cultural Practices Shaping Zoonotic Diseases Surveillance: The Case of Highly Pathogenic Avian Influenza and Thailand Native Chicken Farmers. Transboundary and Emerging Diseases, 64(4), 1294-1305. https://doi.org/10.1111/tbed.12506

Effectiveness of current passive zoonotic disease surveillance systems is limited by the under-reporting of disease outbreaks in the domestic animal population. Evaluating the acceptability of passive surveillance and its economic, social and cultura... Read More about Cultural Practices Shaping Zoonotic Diseases Surveillance: The Case of Highly Pathogenic Avian Influenza and Thailand Native Chicken Farmers.

Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta) (2017)
Journal Article
Suárez-Bonnet, A., Grau-Bassas, E. R., Herráez, P., Quesada-Canales, O., Priestnall, S. L., & De Los Monteros, A. E. (2017). Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta). Journal of Comparative Pathology, 157(2-3), 85-89. https://doi.org/10.1016/j.jcpa.2017.06.009

Naturally occurring mammary tumours are uncommon in prosimians. A 20-year-old female ring-tailed lemur (Lemur catta) developed bilateral enlargement of the mammary glands. Surgical removal revealed that both masses were comprised of multiple nodules... Read More about Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta).

Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella (2017)
Journal Article
Kundu, K., Garg, R., Kumar, S., Mandal, M., Tomley, F. M., Blake, D. P., & Banerjee, P. S. (2017). Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella. Veterinary Parasitology, 244, 44-53. https://doi.org/10.1016/j.vetpar.2017.07.025

Eimeria tenella, the causative agent of caecal coccidiosis, is a pathogenic gut dwelling protozoan which can cause severe morbidity and mortality in farmed chickens. Immune mapped protein-1 (IMP-1) has been identified as an anticoccidial vaccine cand... Read More about Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella.

Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach (2017)
Journal Article
Métras, R., Fournié, G., Dommergues, L., Camacho, A., Cavalerie, L., Mérot, P., …Edmunds, W. J. (2017). Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach. PLoS Neglected Tropical Diseases, 11(7), e0005767. https://doi.org/10.1371/journal.pntd.0005767

Rift Valley fever (RVF) is a major zoonotic and arboviral hemorrhagic fever. The conditions leading to RVF epidemics are still unclear, and the relative role of climatic and anthropogenic factors may vary between ecosystems. Here, we estimate the mos... Read More about Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach.

Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration (2017)
Journal Article
Burkitt, M. D., Williams, J. M., Townsend, T., Hough, R., & Pritchard, D. M. (2017). Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration. https://doi.org/10.1038/cddis.2017.332

Tamoxifen (TAM) has recently been shown to cause acute gastric atrophy and metaplasia in mice. We have previously demonstrated that the outcome of Helicobacter felis infection, which induces similar gastric lesions in mice, is altered by deletion of... Read More about Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration.

The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness (2017)
Journal Article
Walker, M., Pion, S. D. S., Fang, H., Gardon, J., Kamgno, J., Basáñez, M., & Boussinesq, M. (2017). The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness. Clinical Infectious Diseases, 65(12), 2026-2034. https://doi.org/10.1093/cid/cix616

Background: Mass drug administration (MDA) with ivermectin is the cornerstone of efforts to eliminate human onchocerciasis by 2020 or 2025. The feasibility of elimination crucially depends on the effects of multiple ivermectin doses on Onchocerca vol... Read More about The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness.

Economic factors influencing zoonotic disease dynamics: demand for poultry meat and seasonal transmission of avian influenza in Vietnam (2017)
Journal Article
Delabouglise, A., Choisy, M., Phan, T. D., Antoine-Moussiaux, N., Peyre, M., Vu, T. D., …Fournié, G. (2017). Economic factors influencing zoonotic disease dynamics: demand for poultry meat and seasonal transmission of avian influenza in Vietnam. Scientific Reports, 7, 5905. https://doi.org/10.1038/s41598-017-06244-6

While climate is often presented as a key factor influencing the seasonality of diseases, the importance of anthropogenic factors is less commonly evaluated. Using a combination of methods-wavelet analysis, economic analysis, statistical and disease... Read More about Economic factors influencing zoonotic disease dynamics: demand for poultry meat and seasonal transmission of avian influenza in Vietnam.

Herd-level animal management factors associated with the occurrence of bovine neonatal pancytopenia in calves in a multicountry study (2017)
Journal Article
Sauter-Louis, C., Jones, B. A., Henning, J., Stoll, A., Nielen, M., Van Schaik, G., …Pfeiffer, D. U. (2017). Herd-level animal management factors associated with the occurrence of bovine neonatal pancytopenia in calves in a multicountry study. PLoS ONE, 12(7), https://doi.org/10.1371/journal.pone.0179878

Since 2007, mortality associated with a previously unreported haemorrhagic disease has been observed in young calves in several European countries. The syndrome, which has been named ‘bovine neonatal pancytopenia’ (BNP), is characterised by thrombocy... Read More about Herd-level animal management factors associated with the occurrence of bovine neonatal pancytopenia in calves in a multicountry study.

Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle (2017)
Journal Article
Marugan-Hernandez, V., Long, E., Blake, D. P., Crouch, C., & Tomley, F. M. (2017). Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle. https://doi.org/10.1038/s41598-017-04049-1

Eimeria spp. are intracellular parasites that have a major impact on poultry. Effective live vaccines are available and the development of reverse genetic technologies has raised the prospect of using Eimeria spp. as recombinant vectors to express ad... Read More about Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle.

Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014 (2017)
Journal Article
Hernandez-Garcia, J., Wang, J., Restif, O., Holmes, M. A., Mather, A. E., Weinert, L. A., …Tucker, A. W. (2017). Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014. Veterinary Microbiology, 207, 117-124. https://doi.org/10.1016/j.vetmic.2017.06.002

Antimicrobial resistance in Streptococcus suis, a global zoonotic pathogen of pigs, has been mostly studied only in diseased animals using surveys that have not evaluated changes over time. We compared patterns of resistance between S. suis isolat... Read More about Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014.

Optimising cluster survey design for planning schistosomiasis preventive chemotherapy (2017)
Journal Article
Knowles, S. C. L., Sturrock, H. J. W., Turner, H., Whitton, J. M., Gower, C. M., Jemu, S., …Fleming, F. M. (2017). Optimising cluster survey design for planning schistosomiasis preventive chemotherapy. PLoS Neglected Tropical Diseases, 11(5), https://doi.org/10.1371/journal.pntd.0005599

We used baseline schistosomiasis mapping surveys from three countries (Malawi, Côte d’Ivoire and Liberia) to generate spatially realistic gold standard datasets, against which we tested alternative two-stage cluster survey designs. We assessed how sa... Read More about Optimising cluster survey design for planning schistosomiasis preventive chemotherapy.

Socio-demographic determinants of Toxoplasma gondii seroprevalence in migrant workers of Peninsular Malaysia (2017)
Journal Article
Sahimin, N., Lim, Y. A. L., Ariffin, F., Behnke, J. M., Basáñez, M., Walker, M., …Mohd Zain, S. N. (2017). Socio-demographic determinants of Toxoplasma gondii seroprevalence in migrant workers of Peninsular Malaysia. https://doi.org/10.1186/s13071-017-2167-8

The number of migrants working in Malaysia has increased sharply since the 1970’s and there is concern that infectious diseases endemic in other (e.g. neighbouring) countries may be inadvertently imported. Compulsory medical screening prior to enteri... Read More about Socio-demographic determinants of Toxoplasma gondii seroprevalence in migrant workers of Peninsular Malaysia.