Challenges in defining the functional, non‐coding, expressed genome of members of the Mycobacterium tuberculosis complex (2021)
Journal Article
Stiens, J., Arnvig, K. B., Kendall, S. L., & Nobeli, I. (2022). Challenges in defining the functional, non‐coding, expressed genome of members of the Mycobacterium tuberculosis complex. Molecular Microbiology, 117(1), 20-31. https://doi.org/10.1111/mmi.14862

A definitive transcriptome atlas for the non-coding expressed elements of the members of the Mycobacterium tuberculosis complex (MTBC) does not exist. Incomplete lists of non-coding transcripts can be obtained for some of the reference genomes (e.g.,... Read More about Challenges in defining the functional, non‐coding, expressed genome of members of the Mycobacterium tuberculosis complex.

Probing differences in gene essentiality between the human and animal adapted (2021)
Journal Article
Gibson, A. J., Passmore, I. J., Faulkner, V., Xia, D., Nobeli, I., Stiens, J., …Kendall, S. L. (2021). Probing differences in gene essentiality between the human and animal adapted. Frontiers in Veterinary Science,

Members of the Mycobacterium tuberculosis complex (MTBC) show distinct host adaptations, preferences and phenotypes despite being >99% identical at the nucleic acid level. Previous studies have explored gene expression changes between the members, ho... Read More about Probing differences in gene essentiality between the human and animal adapted.

A Practical Guide To The Design Implementation And Evaluation Stages Of Food Safety Nudges (2021)
Report
Hennessey, M., Unger, F., Sinh, D. X., Phuc, P. D., Tuan Hai, N. H., Thanh Huyen, L. T., …Hasler, B. (2021). A Practical Guide To The Design Implementation And Evaluation Stages Of Food Safety Nudges. Addis Ababa: International Livestock Research Institute

The field of nudge theory – influencing the way people make choices through subtle environmental change – has been used to improve healthy food choices, but to date has not been extensively applied to the livestock and food chain sector. In this... Read More about A Practical Guide To The Design Implementation And Evaluation Stages Of Food Safety Nudges.

Tuberculosis in badgers where the bovine tuberculosis epidemic is expanding in cattle in England (2021)
Journal Article
Swift, B. M. C., Sandoval Barron, E., Christley, R., Corbetta, D., Grau-Roma, L., Jewell, C., …Bennett, M. (2021). Tuberculosis in badgers where the bovine tuberculosis epidemic is expanding in cattle in England. Scientific Reports, https://doi.org/10.1038/s41598-021-00473-6

Bovine tuberculosis (bTB) is an important animal health and economic problem for the cattle industry and a potential zoonotic threat. Wild badgers (Meles meles) play a role on its epidemiology in some areas of high prevalence in cattle, particularly... Read More about Tuberculosis in badgers where the bovine tuberculosis epidemic is expanding in cattle in England.

A global media analysis of the impact of the COVID-19 pandemic on chicken meat food systems: Key vulnerabilities and opportunities for building resilience (2021)
Journal Article
Whatford, L., Chapot, L., Compston, P., Tak, M., Cuevas, S., Garza, M., …Haesler, B. (2021). A global media analysis of the impact of the COVID-19 pandemic on chicken meat food systems: Key vulnerabilities and opportunities for building resilience. Sustainability, https://doi.org/10.3390/su13169435

Food systems are increasingly under threat, with climate, biological, economic or policy shocks and stressors occurring at an increasing frequency and scale. News articles published globally between December 2019 and April 2020 were collated and anal... Read More about A global media analysis of the impact of the COVID-19 pandemic on chicken meat food systems: Key vulnerabilities and opportunities for building resilience.

Molecular basis for DarT ADP-ribosylation of a DNA base (2021)
Journal Article
Schuller, M., Butler, R., Ariza, A., Tromans-Coia, C., Jankevicius, G., Claridge, T., …Ahel, I. (2021). Molecular basis for DarT ADP-ribosylation of a DNA base. Nature, https://doi.org/10.1038/s41586-021-03825-4

ADP-ribosyltransferases (ARTs) utilise NAD+ to catalyse substrate ADP-ribosylation, thereby regulating cellular pathways or contributing to toxin-mediated pathogenicity of bacteria. Reversible ADP-ribosylation has traditionally been considered a prot... Read More about Molecular basis for DarT ADP-ribosylation of a DNA base.

Using Qualitative System Dynamics Analysis to Promote Inclusive Livestock Value Chains: A Case Study of the South African Broiler Value Chain (2021)
Journal Article
Cuevas Garcia-Dorado, S., Queenan, K., Shankar, B., Häsler, B., Mabhaudhi, T., Cooper, G., & Slotow, R. (in press). Using Qualitative System Dynamics Analysis to Promote Inclusive Livestock Value Chains: A Case Study of the South African Broiler Value Chain. Frontiers in Sustainable Food Systems, 5, https://doi.org/10.3389/fsufs.2021.670756

Livestock value chains globally are increasingly dualistic, with integrated market-leaders co-existing with comparatively disadvantaged small producers who, nevertheless, support rural livelihoods and food access, and can also contribute to more resi... Read More about Using Qualitative System Dynamics Analysis to Promote Inclusive Livestock Value Chains: A Case Study of the South African Broiler Value Chain.

Development of a Method to Detect Mycobacterium paratuberculosis in the Blood of Farmed Deer Using Actiphage® Rapid (2021)
Journal Article
Kubala, A., Perehinec, T. M., Evans, C., Pirovano, A., Swift, B. M. C., & Rees, C. E. D. (2021). Development of a Method to Detect Mycobacterium paratuberculosis in the Blood of Farmed Deer Using Actiphage® Rapid. Frontiers in Veterinary Science, 8, https://doi.org/10.3389/fvets.2021.665697

Mycobacterium avium subsp paratuberculosis (MAP) is the causative agent of Johne's disease, which is an economically and clinically relevant pathogen for commercial deer production. The purpose of this study was to develop a method that could be used... Read More about Development of a Method to Detect Mycobacterium paratuberculosis in the Blood of Farmed Deer Using Actiphage® Rapid.

Assessment of evaluation tools for integrated surveillance of antimicrobial use and resistance based on selected case studies (2021)
Journal Article
Bennani, H., Sandberg, M., Hesp, A., Aenishaenslin, C., Bordier, M., Bergwerff, U., …Alban, L. (2021). Assessment of evaluation tools for integrated surveillance of antimicrobial use and resistance based on selected case studies. Frontiers in Veterinary Science, https://doi.org/10.3389/fvets.2021.620998

Regular evaluation of integrated surveillance for antimicrobial use (AMU) and resistance (AMR) in animals, humans and the environment is needed to ensure system effectiveness, but the question is how. In this study, six different evaluation tools wer... Read More about Assessment of evaluation tools for integrated surveillance of antimicrobial use and resistance based on selected case studies.

Building an ecologically founded disease risk prioritization framework for migratory wildlife species based on contact with livestock (2021)
Journal Article
Khanyari, M., Robinson, S., E., M., Singh N. J., Brown, T., Salemgareyev, A., …Kock, R. (in press). Building an ecologically founded disease risk prioritization framework for migratory wildlife species based on contact with livestock. Journal of Applied Ecology, 00, 1-16. https://doi.org/10.1111/1365-2664.13937

Coccidiosis, caused by Eimeria species parasites, remains a major threat to poultry production, undermining economic performance and compromising welfare. The recent characterization of three new Eimeria species that infect chickens has highlighted t... Read More about Building an ecologically founded disease risk prioritization framework for migratory wildlife species based on contact with livestock.

Review of Peste des Petits Ruminants Occurrence and Spread in Tanzania (2021)
Journal Article
Mdetele, D., Komba, E., Misago, S., Misinzo, G., Kock, R., & Jones, B. (2021). Review of Peste des Petits Ruminants Occurrence and Spread in Tanzania. Animals, 11(6), https://doi.org/10.3390/ani11061698

Peste des petits ruminants (PPR) is an important transboundary disease of domestic small ruminants, camels and wild artiodactyls. The disease has significant socioeconomic impacts on communities that depend on livestock for their livelihood, and is a... Read More about Review of Peste des Petits Ruminants Occurrence and Spread in Tanzania.

Serologic responses correlate with current but not future bacterial shedding in badgers naturally infected with Mycobacterium bovis (2021)
Journal Article
Jolma, E. R., Delahay, R. J., Smith, F., & Drewe, J. A. (in press). Serologic responses correlate with current but not future bacterial shedding in badgers naturally infected with Mycobacterium bovis. Transboundary and Emerging Diseases, https://doi.org/10.1111/tbed.14181

Bovine tuberculosis is a challenging cattle disease with substantial economic costs in affected countries. Eradication in parts of the United Kingdom and Ireland is hindered by transmission of the causative agent Mycobacterium bovis between cattle an... Read More about Serologic responses correlate with current but not future bacterial shedding in badgers naturally infected with Mycobacterium bovis.

Peste des petits ruminants virus infection at the wildlife-livestock interface in the Greater Serengeti ecosystem, 2015-2019 (2021)
Journal Article
Jones, B. A., Mahapatra, M., Mdetele, D., Keyyu, J., Gakuya, F., Eblate, E., …Kock, R. (2021). Peste des petits ruminants virus infection at the wildlife-livestock interface in the Greater Serengeti ecosystem, 2015-2019. Viruses,

Peste des petits ruminants (PPR) is a viral disease of goats and sheep that occurs in Africa, the Middle East and Asia with severe impact on livelihoods and livestock trade. Many wild artiodactyls are susceptible to PPR virus (PPRV) infection, and so... Read More about Peste des petits ruminants virus infection at the wildlife-livestock interface in the Greater Serengeti ecosystem, 2015-2019.

Systems-thinking approach to identify and assess feasibility of potential interventions to reduce antibiotic use in tilapia farming in Egypt (2021)
Journal Article
Desbois, A., Garza, M., Eltholth, M., Hegazy, Y., Mateus, A., Adams, A., …Brunton, L. (in press). Systems-thinking approach to identify and assess feasibility of potential interventions to reduce antibiotic use in tilapia farming in Egypt. Aquaculture,

Zoonotic disease preparedness in sub-Saharan African countries (2021)
Journal Article
Elton, L., And the PANDORA-ID-NET consortium, Haider, N., Kock, R., Thomason, M. J., Tembo, J., …McHugh, T. D. (2021). Zoonotic disease preparedness in sub-Saharan African countries. One Health Outlook, 3(5), 1-9. https://doi.org/10.1186/s42522-021-00037-8

Background: The emergence of high consequence pathogens such as Ebola and SARS-CoV-2, along with the continued burden of neglected diseases such as rabies, has highlighted the need for preparedness for emerging and endemic infectious diseases of zoon... Read More about Zoonotic disease preparedness in sub-Saharan African countries.

Zoonotic tuberculosis — The changing landscape (2021)
Journal Article
Kock, R., Kock, R., Michel, A. L., Haider, N., Yeboah-Manu, D., Brunton, L., …Zumla, A. (2021). Zoonotic tuberculosis — The changing landscape. International Journal of Infectious Diseases, https://doi.org/10.1016/j.ijid.2021.02.091

Despite slow reductions in the annual burden of active human tuberculosis (TB) cases, zoonotic TB (zTB) remains a poorly monitored and an important unaddressed global problem. There is a higher incidence in some regions and countries, especially wh... Read More about Zoonotic tuberculosis — The changing landscape.

Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits (2021)
Journal Article
Kendall, S. L., Faulkner, V., Cox, A. A., Goh, S., van Bohemen, A., Gibson, A. J., …Willcocks, S. (in press). Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits. Frontiers in Microbiology, 11, https://doi.org/10.3389/fmicb.2020.619427

A greater understanding of the genes involved in antibiotic resistance in Mycobacterium tuberculosis (Mtb) is necessary for the design of improved therapies. Clustered regularly interspaced short palindromic repeat interference (CRISPRi) has been pre... Read More about Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits.

A Cohort Study Risk Factor Analysis for Endemic Disease in Pre- weaned Dairy Heifer Calves (2021)
Journal Article
Johnson, K. F., Chancellor, N., & Wathes, D. C. (in press). A Cohort Study Risk Factor Analysis for Endemic Disease in Pre- weaned Dairy Heifer Calves. Animals, https://doi.org/10.3390/xxxxx

Simple Summary: Most dairy heifer calves are removed from their dam and reared on milk from birth until weaning at around nine weeks of age. During this period they are susceptible to diseases which reduce their welfare and later performance in the d... Read More about A Cohort Study Risk Factor Analysis for Endemic Disease in Pre- weaned Dairy Heifer Calves.