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Sost deficiency does not alter bone’s lacunar or vascular porosity in mice (2017)
Journal Article
Mosey, H., Núñez, J. A., Goring, A., Clarkin, C. E., Staines, K. A., Lee, P. D., …Javaheri, B. (2017). Sost deficiency does not alter bone’s lacunar or vascular porosity in mice. Frontiers in Materials, 4(27), https://doi.org/10.3389/fmats.2017.00027

SCLEROSTIN (Sost) is expressed predominantly in osteocytes acting as a negative regulator of bone formation. In humans, mutations in the SOST gene lead to skeletal overgrowth and increased bone mineral density, suggesting that SCLEROSTIN is a key reg... Read More about Sost deficiency does not alter bone’s lacunar or vascular porosity in mice.

Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers (2017)
Journal Article
Packer, R. M. A., Volk, H. A., & Fowkes, R. C. (2017). Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers. Physiology and Behavior, 177, 27-33. https://doi.org/10.1016/j.physbeh.2017.04.008

There is a complex bidirectional relationship between stress and epilepsy. Stressful stimuli and subsequent cortisol release act as a trigger for seizure activity in some individuals with epilepsy, and seizure activity itself may act as a stressor to... Read More about Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers.

Alterations in thoracolumbosacral movement when pain causing lameness has been improved by diagnostic analgesia (2017)
Journal Article
Greve, L., Dyson, S., & Pfau, T. (2017). Alterations in thoracolumbosacral movement when pain causing lameness has been improved by diagnostic analgesia. The Veterinary Journal, 224, 5-3. https://doi.org/10.1016/j.tvjl.2017.03.009

Lameness, thoracolumbosacral pain and reduced range of motion (ROM) often coexist; better understanding of their relationship is needed. The objectives were to determine if thoracolumbosacral movement of horses changes when pain causing lameness is i... Read More about Alterations in thoracolumbosacral movement when pain causing lameness has been improved by diagnostic analgesia.

Clinical reasoning in feline epilepsy: Which combination of clinical information is useful? (2017)
Journal Article
Stanciu, G. D., Packer, R. M. A., Pakozdy, A., Solcan, G., & Volk, H. A. (2017). Clinical reasoning in feline epilepsy: Which combination of clinical information is useful?. https://doi.org/10.1016/j.tvjl.2017.04.001

We sought to identify the association between clinical risk factors and the diagnosis of idiopathic epilepsy (IE) or structural epilepsy (SE) in cats, using statistical models to identify combinations of discrete parameters from the patient signalmen... Read More about Clinical reasoning in feline epilepsy: Which combination of clinical information is useful?.

Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner (2017)
Journal Article
Rhodin, M., Egenvall, A., Haubro Andersen, P., & Pfau, T. (2017). Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner. PLoS ONE, 12(4), e0176253. https://doi.org/10.1371/journal.pone.0176253

Recent studies evaluating horses in training and considered free from lameness by their owners have identified a large proportion of horses with motion asymmetries. However the prevalence, type and magnitude of asymmetries when trotting in a straight... Read More about Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner.

Investigation looking at the repeatability of 20 Society of Master Saddlers (SMS) qualified saddle fitters’ observations during static saddle fit (2017)
Journal Article
Guire, R., Weller, R., Fisher, M., & Beavis, J. (2017). Investigation looking at the repeatability of 20 Society of Master Saddlers (SMS) qualified saddle fitters’ observations during static saddle fit. Journal of Equine Veterinary Science, 56, 1-5. https://doi.org/10.1016/j.jevs.2017.04.001

Saddle fit is widely considered to be a crucial factor for the health and performance of riding horses; however, there have been no studies looking at the agreement between professionals who fit and assess saddles. The aim of the study was to determi... Read More about Investigation looking at the repeatability of 20 Society of Master Saddlers (SMS) qualified saddle fitters’ observations during static saddle fit.

Progressive Structural Defects in Canine Centronuclear Myopathy Indicate a Role for HACD1 in Maintaining Skeletal Muscle Membrane Systems (2017)
Journal Article
Walmsley, G. L., Blott, S., Venner, K., Sewry, C., Laport, J., Blondelle, J., …Piercy, R. J. (2017). Progressive Structural Defects in Canine Centronuclear Myopathy Indicate a Role for HACD1 in Maintaining Skeletal Muscle Membrane Systems. American Journal of Pathology, 187(2), 441-456. https://doi.org/10.1016/j.ajpath.2016.10.002

Mutations in HACD1/PTPLA cause recessive congenital myopathies in humans and dogs. Hydroxyacyl-coA dehydratases are required for elongation of very long chain fatty acids, and HACD1 has a role in early myogenesis, but the functions of this striated m... Read More about Progressive Structural Defects in Canine Centronuclear Myopathy Indicate a Role for HACD1 in Maintaining Skeletal Muscle Membrane Systems.