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Clinical reasoning in feline epilepsy: Which combination of clinical information is useful?

Stanciu, G D; Packer, R M A; Pakozdy, A; Solcan, G; Volk, H A

Authors

G D Stanciu

R M A Packer

A Pakozdy

G Solcan

H A Volk



Abstract

We sought to identify the association between clinical risk factors and the diagnosis of idiopathic epilepsy (IE) or structural epilepsy (SE) in cats, using statistical models to identify combinations of discrete parameters from the patient signalment, history and neurological examination findings that could suggest the most likely diagnosis. Data for 138 cats with recurrent seizures were reviewed, of which 110 were valid for inclusion. Seizure aetiology was classified as IE in 57% and SE in 43% of cats. Binomial logistic regression analyses demonstrated that pedigree status, older age at seizure onset (particularly >7 years old), abnormal neurological examinations, and ictal vocalisation were associated with a diagnosis of SE compared to IE, and that ictal salivation was more likely to be associated with a diagnosis of IE than SE. These findings support the importance of considering inter-ictal neurological deficits and seizure history in clinical reasoning.

Citation

Stanciu, G. D., Packer, R. M. A., Pakozdy, A., Solcan, G., & Volk, H. A. (2017). Clinical reasoning in feline epilepsy: Which combination of clinical information is useful?. https://doi.org/10.1016/j.tvjl.2017.04.001

Journal Article Type Article
Acceptance Date Apr 8, 2017
Publication Date May 2, 2017
Deposit Date Aug 25, 2017
Publicly Available Date May 29, 2018
Journal VETERINARY JOURNAL
Peer Reviewed Peer Reviewed
Volume 225
Pages 9-12
DOI https://doi.org/10.1016/j.tvjl.2017.04.001
Public URL https://rvc-repository.worktribe.com/output/1392083