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Bovine Endometrial Cells Mount Innate Immune Response to the Intracellular Ligands CL097 and Poly(dA:dT) Indicating Roles against Uterine Viruses (2017)
Journal Article
Oguejiofor, C. F., Cheng, Z. R., Fouladi-Nashta, A. A., & Wathes, D. C. (2017). Bovine Endometrial Cells Mount Innate Immune Response to the Intracellular Ligands CL097 and Poly(dA:dT) Indicating Roles against Uterine Viruses. Open Journal of Animal Sciences, 7(2), https://doi.org/10.4236/ojas.2017.72010

Uterine infection and endometritis cause infertility and economic losses in the cattle industry. The innate immune response of the endometrium is critical in the elimination of pathogenic organisms that invade the uterus in postpartum cows. This stud... Read More about Bovine Endometrial Cells Mount Innate Immune Response to the Intracellular Ligands CL097 and Poly(dA:dT) Indicating Roles against Uterine Viruses.

Hyaluronan and Hyaluronidase, which is better for embryo development? (2016)
Journal Article
Marei, W. F. A., Raheem, K. A., Salavati, M., Tremaine, T., Khalid, M., & Fouladi-Nashta, A. A. (2016). Hyaluronan and Hyaluronidase, which is better for embryo development?. Theriogenology, 86(4), 940-948. https://doi.org/10.1016/j.theriogenology.2016.03.017

Our aim was to examine size-specific effects of Hyaluronan (HA) on preimplantation embryo development. We investigated the effects of Hyalovet (HA, 500–750 kDa; the size produced by HA synthase-3, which is abundant in the oviduct), or HA treated with... Read More about Hyaluronan and Hyaluronidase, which is better for embryo development?.

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide (2015)
Journal Article
Oguejiofor, C. F., Cheng, Z. R., Abudureyimu, A., Anstaett, O. L., Brownlie, J., Fouladi-Nashta, A. A., & Wathes, D. C. (2015). Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide. Biology of Reproduction, 93(4), https://doi.org/10.1095/biolreprod.115.128876

Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial... Read More about Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide.

Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity (2015)
Journal Article
Oguejiofor, C. F., Cheng, Z. R., Abudureyimu, A., Fouladi-Nashta, A. A., & Wathes, D. C. (2015). Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity. Biology of Reproduction, 93(4), https://doi.org/10.1095/biolreprod.115.128868

The dysregulation of endometrial immune response to bacterial lipopolysaccharide (LPS) has been implicated in uterine disease and infertility in the postpartum dairy cow, although the mechanisms are not clear. Here, we investigated whole-transcriptom... Read More about Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity.

Influence of energy balance on the antimicrobial peptides S100A8 and S100A9 in the endometrium of the postpartum dairy cow (2013)
Journal Article
Swangchan-Uthai, T., Chen, Q., Kirton, S. E., Fenwick, M. A., Cheng, Z. R., Paton, J., …Wathes, D. C. (2013). Influence of energy balance on the antimicrobial peptides S100A8 and S100A9 in the endometrium of the postpartum dairy cow. Reproduction, 145(5), 527-539. https://doi.org/10.1530/REP-12-0513

Uterine inflammation occurs after calving in association with extensive endometrial remodelling and bacterial contamination. If the inflammation persists, it leads to reduced fertility. Chronic endometritis is highly prevalent in high-yielding cows t... Read More about Influence of energy balance on the antimicrobial peptides S100A8 and S100A9 in the endometrium of the postpartum dairy cow.