Rat osteoblast cultures
Journal Article
Orriss, I. R., Taylor, S. E., & Arnett, T. R. Rat osteoblast cultures. https://doi.org/10.1007/978-1-61779-415-5_3
Outputs (38)
The regulation of osteoblast function and bone mineralisation by extracellular nucleotides: The role of p2x receptors
Journal Article
Orriss, I. R., Key, M. L., Brandao-Burch, A., Patel, J. J., Burnstock, G., & Arnett, T. R. The regulation of osteoblast function and bone mineralisation by extracellular nucleotides: The role of p2x receptors. BONE, 51(3), 389-400. https://doi.org/10.1016/j.bone.2012.06.013
Rodent osteoclast cultures
Journal Article
Orriss, I. R., & Arnett, T. R. Rodent osteoclast cultures. https://doi.org/10.1007/978-1-61779-415-5_8
The P2X7 receptor is an important regulator of extracellular ATP levels
Journal Article
Brandao-Burch, A., Key, M. L., Patel, J. J., Arnett, T. R., & Orriss, I. R. The P2X7 receptor is an important regulator of extracellular ATP levels. Frontiers in Endocrinology, 3(41), https://doi.org/10.3389/fendo.2012.00041
Role of the P2Y13 receptor in the differentiation of bone marrow stromal cells into osteoblasts and adipocytes
Journal Article
Biver, G., Wang, N., Gartland, A., Orriss, I. R., Arnett, T. R., Boeynaems, J. M., & Robaye, B. Role of the P2Y13 receptor in the differentiation of bone marrow stromal cells into osteoblasts and adipocytes. STEM CELLS, https://doi.org/10.1002/stem.1411
Extracellular ATP released by osteoblasts is a key local inhibitor of bone mineralisation
Journal Article
Orriss, I. R., Key, M. L., Hajjawi, M. O. R., & Arnett, T. R. (in press). Extracellular ATP released by osteoblasts is a key local inhibitor of bone mineralisation. PLoS ONE, 8(7), e69057. https://doi.org/10.1371/journal.pone.0069057Previous studies have shown that exogenous ATP (>1µM) prevents bone formation in vitro by blocking mineralisation of the collagenous matrix. This effect is thought to be mediated via both P2 receptor-dependent pathways and a receptor-independent mech... Read More about Extracellular ATP released by osteoblasts is a key local inhibitor of bone mineralisation.
Generation of rodent and human osteoblasts
Journal Article
Taylor, S. E., Shah, M., & Orriss, I. R. Generation of rodent and human osteoblasts. https://doi.org/10.1038/bonekey.2014.80
FIBRILLIN-1 EXPRESSION, WHICH REGULATES OF TGF-B BIOAVAILABILITY, IS MODIFIED DURING OSTEOARTHRITIS AND MUTATIONS LEAD TO OSTEOARTHRITIS
Journal Article
Ramanayake, W., Jones, H., Orriss, I. R., Arnett, T., Pitsillides, A. A., Denton, C., …Poulet, B. FIBRILLIN-1 EXPRESSION, WHICH REGULATES OF TGF-B BIOAVAILABILITY, IS MODIFIED DURING OSTEOARTHRITIS AND MUTATIONS LEAD TO OSTEOARTHRITIS. Osteoarthritis and Cartilage, 22, S141-S141
THE REGULATION OF SKELETAL AND SOFT TISSUE MINERALIZATION BY ATP AND NPP1
Journal Article
Orriss, I. R., Hajjawi, M. O. R., & Arnett, T. R. THE REGULATION OF SKELETAL AND SOFT TISSUE MINERALIZATION BY ATP AND NPP1. Purinergic Signalling, 10(4), 704-704. https://doi.org/10.1007/s11302-014-9430-7
Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures
Journal Article
Wornham, D. P., Hajjawi, M. O. R., Orriss, I. R., & Arnett, T. R. (in press). Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures. Osteoporosis International, 25(10), 2477-2484. https://doi.org/10.1007/s00198-014-2791-5The basic mechanisms by which strontium ranelate acts on bone are still unclear. We show that an important action of strontium salts is to block calcification in cultures of osteoblasts, the bone-forming cells. These results suggest that strontium tr... Read More about Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures.