Outputs (123)

A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling (2017)
Journal Article
Gatliff, J., East, D. A., Singh, A., Alvarez, M. S., Frison, M., Matic, I., …Campanella, M. (2017). A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling. https://doi.org/10.1038/cddis.2017.186

The 18 kDa translocator protein TSPO localizes on the outer mitochondrial membrane (OMM). Systematically overexpressed at sites of neuroinflammation it is adopted as a biomarker of brain conditions. TSPO inhibits the autophagic removal of mitochondri... Read More about A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling.

Morphology and the gradient of a symmetric potential predicts gait transitions of dogs (2017)
Journal Article
Wilshin, S. D., Haynes, G. C., Porteous, J., Koditschek, D., Revzen, S., & Spence, A. J. (2017). Morphology and the gradient of a symmetric potential predicts gait transitions of dogs. Biological Cybernetics, 111(3-4), 269-277. https://doi.org/10.1007/s00422-017-0721-2

Gaits and gait transitions play a central role in the movement of animals. Symmetry is thought to govern the structure of the nervous system, and constrain the limb motions of quadrupeds. We quantify the symmetry of dog gaits with respect to combinat... Read More about Morphology and the gradient of a symmetric potential predicts gait transitions of dogs.

Beneficial effects of melatonin on in vitro embryo production from juvenile goat oocytes (2017)
Journal Article
Soto-Heras, S., Roura, M., Catalá, M. G., Menéndez-Blanco, I., Izquierdo, D., Fouladi-Nashta, A. A., & Paramio, M. T. (2017). Beneficial effects of melatonin on in vitro embryo production from juvenile goat oocytes. https://doi.org/10.1071/RD17170

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study (2017)
Journal Article
Noyce, A. J., Kia, D. A., Hemani, G., Nicolas, A., Price, T. R., De Pablo-Fernandez, E., …Wood, N. W. (2017). Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study. PLoS Medicine, 14(6), https://doi.org/10.1371/journal.pmed.1002314

Both positive and negative associations between higher body mass index (BMI) and Parkinson disease (PD) have been reported in observational studies, but it has been difficult to establish causality because of the possibility of residual confounding o... Read More about Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.

Breed, Coat Color, and Hair Length as Risk Factors for Hyperthyroidism in Cats (2017)
Journal Article
Crossley, V. J., Debnath, A., Chang, Y. M., Fowkes, R. C., Elliott, J., & Syme, H. M. (2017). Breed, Coat Color, and Hair Length as Risk Factors for Hyperthyroidism in Cats. Journal of Veterinary Internal Medicine, 31(4), 1028-1034. https://doi.org/10.1111/jvim.14737

Hyperthyroidism is very common in older cats, but the etiopathogenesis is poorly understood. Decreased risk of hyperthyroidism has been reported in certain colorpoint breeds, and this observation previously has been hypothesized to result from relati... Read More about Breed, Coat Color, and Hair Length as Risk Factors for Hyperthyroidism in Cats.

Regulation of bone mineral density in the grey squirrel, Sciurus carolinensis: Bioavailability of calcium oxalate, and implications for bark stripping (2017)
Journal Article
Nichols, C. P., Gregory, N. G., Goode, N., Gill, R. M. A., & Drewe, J. A. (2017). Regulation of bone mineral density in the grey squirrel, Sciurus carolinensis: Bioavailability of calcium oxalate, and implications for bark stripping. Journal of Animal Physiology and Animal Nutrition, 102(1), https://doi.org/10.1111/jpn.12740

Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich (2017)
Journal Article
Chadwick, K., Shefelbine, S. J., Pitsillides, A. A., & Hutchinson, J. R. (2017). Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich. Royal Society Open Science, 4(6), 170133. https://doi.org/10.1098/rsos.170133

The appearance and shape of sesamoid bones within a tendon or ligament wrapping around a joint are understood to be influenced by both genetic and epigenetic factors. Ostriches (Struthio camelus) possess two sesamoid patellae (kneecaps), one of which... Read More about Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich.

Cavalier King Charles Spaniels with Chiari-like malformation and Syringomyelia have increased variability of spatio-temporal gait characteristics (2017)
Journal Article
Olsen, E., Suiter, E. J., Pfau, T., McGonnell, I. M., Matiasek, K., Giejda, A., & Volk, H. A. (2017). Cavalier King Charles Spaniels with Chiari-like malformation and Syringomyelia have increased variability of spatio-temporal gait characteristics. BMC Veterinary Research, 13(159), https://doi.org/10.1186/s12917-017-1077-5

The STR/ort mouse model of spontaneous osteoarthritis – an update (2017)
Journal Article
Staines, K. A., Poulet, B., Wentworth, D. N., & Pitsillides, A. A. (2017). The STR/ort mouse model of spontaneous osteoarthritis – an update. Osteoarthritis and Cartilage, 25(6), 802-808. https://doi.org/10.1016/j.joca.2016.12.014

Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release (2017)
Journal Article
Orriss, I. R., Gueneri, D., Hajjawai, M. O., Shaw, K., Patel, J. J., & Arnett, T. R. (2017). Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release. Journal of Endocrinology, 233, 341-356. https://doi.org/10.1530/JOE-17-0042

Bone cells constitutively release ATP into the extracellular environment where it acts locally via P2 receptors to regulate bone cell function. Whilst P2Y2 receptor stimulation regulates bone mineralisation, the functional effects of this receptor in... Read More about Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release.