Outputs (104)

Evolutionary integration and modularity in the archosaur cranium (2019)
Journal Article
Felice, R. N., Watanabe, A., Cuff, A. R., Noirault, E., Pol, D., Witmer, L. M., …Goswami, A. (2019). Evolutionary integration and modularity in the archosaur cranium. Integrative and Comparative Biology, https://doi.org/10.1093/icb/icz052

Complex structures, like the vertebrate skull, are composed of numerous elements or traits that must develop and evolve in a coordinated manner to achieve multiple functions. The strength of association among phenotypic traits (i.e., integration), an... Read More about Evolutionary integration and modularity in the archosaur cranium.

What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol (2019)
Journal Article
Packer, R. M. A., Davies, A. M., Volk, H. A., Puckett, H. L., Hobbs, S. L., & Fowkes, R. C. (2019). What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol. PLoS ONE, 14(5), e0216000. https://doi.org/10.1371/journal.pone.0216000

Hair is an emerging biological matrix in which to measure chronic HPA axis activity, offering a longer term view into an animal’s life. We explored effects of exogenous (e.g. lifestyle, medications, social environment) and endogenous (e.g. disease, b... Read More about What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol.

Ontogenetic changes in the body plan of the sauropodomorph dinosaur Mussaurus patagonicus reveal shifts of locomotor stance during growth (2019)
Journal Article
Otero, A., Cuff, A. R., Allen, V., Sumner-Rooney, L., Pol, D., & Hutchinson, J. R. (2019). Ontogenetic changes in the body plan of the sauropodomorph dinosaur Mussaurus patagonicus reveal shifts of locomotor stance during growth. https://doi.org/10.1038/s41598-019-44037-1

Ontogenetic information is crucial to understand life histories and represents a true challenge in dinosaurs due to the scarcity of growth series available. Mussaurus patagonicus was a sauropodomorph dinosaur close to the origin of Sauropoda known fr... Read More about Ontogenetic changes in the body plan of the sauropodomorph dinosaur Mussaurus patagonicus reveal shifts of locomotor stance during growth.

Foot pressure distribution in White Rhinoceroses (Ceratotherium simum) during walking (2019)
Journal Article
Panagiotopoulou, O., Pataky, T. C., & Hutchinson, J. R. (2019). Foot pressure distribution in White Rhinoceroses (Ceratotherium simum) during walking. PeerJ, 7, e6881. https://doi.org/10.7717/peerj.6881

White rhinoceroses (Ceratotherium simum) are odd-toed ungulates that belong to the group Perissodactyla. Being second only to elephants in terms of large body mass amongst extant tetrapods, rhinoceroses make fascinating subjects for the study of how... Read More about Foot pressure distribution in White Rhinoceroses (Ceratotherium simum) during walking.

Exploring mitochondrial cholesterol (mChol) signalling for therapeutic intervention in neurological conditions (2019)
Journal Article
Desai, R., & Campanella, M. (2019). Exploring mitochondrial cholesterol (mChol) signalling for therapeutic intervention in neurological conditions. British Journal of Pharmacology, https://doi.org/10.1111/bph.14697

The pharmacological targeting of cholesterol levels continues to draw interest due to the vast success of therapeutics such as statins in extending life expectancy by modifying the prognosis of diseases associated with the impairment of the lipid met... Read More about Exploring mitochondrial cholesterol (mChol) signalling for therapeutic intervention in neurological conditions.

High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia (2019)
Journal Article
Yurchenko, A. A., Deniskova, T. E., Yudin, N. S., Dotsev, A. V., Khamiruev, T. N., Selionova, M. I., …Larkin, D. M. (2019). High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia. BMC Genomics, 20(Suppl 3), https://doi.org/10.1186/s12864-019-5537-0

Domestication and centuries of selective breeding have changed genomes of sheep breeds to respond to environmental challenges and human needs. The genomes of local breeds, therefore, are valuable sources of genomic variants to be used to understand m... Read More about High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia.

Evolutionary parallelisms of pectoral and pelvic network-anatomy from fins to limbs (2019)
Journal Article
Esteve-Altava, B., Pierce, S. E., Molnar, J. L., Johnston, P., Diogo, R., & Hutchinson, J. R. (2019). Evolutionary parallelisms of pectoral and pelvic network-anatomy from fins to limbs. Science Advances, 5(5), https://doi.org/10.1126/sciadv.aau7459

Lobe-fins transformed into limbs during the Devonian period, facilitating the water-to-land transition in tetrapods. We traced the evolution of well-articulated skeletons across the fins-to-limbs transition, using a network-based approach to quantify... Read More about Evolutionary parallelisms of pectoral and pelvic network-anatomy from fins to limbs.

The impact of pelvic lateral rotation on hindlimb kinematics and stride length in the red-legged running frog, Kassina maculata (2019)
Journal Article
Collings, A. J., Porro, L. B., Hill, C., & Richards, C. T. (2019). The impact of pelvic lateral rotation on hindlimb kinematics and stride length in the red-legged running frog, Kassina maculata. Royal Society Open Science, 6, 190060. https://doi.org/10.1098/rsos.190060

Some frog species, such as Kassina maculata (red-legged running frog), use an asynchronous walking/running gait as their primary locomotor mode. Prior comparative anatomy work has suggested that lateral rotation of the pelvis improves walking perform... Read More about The impact of pelvic lateral rotation on hindlimb kinematics and stride length in the red-legged running frog, Kassina maculata.

FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy (2019)
Journal Article
Soutar, M. P. M., Kempthorne, L., Annuario, E., Luft, C., Wray, S., Ketteler, R., …Plun-Favreau, H. (2019). FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy. Autophagy, https://doi.org/10.1080/15548627.2019.1603549

Mitochondrial quality control is essential for maintaining a healthy population of mitochondria. Two proteins associated with Parkinson disease, the kinase PINK1 and the E3 ubiquitin ligase PRKN, play a central role in the selective degradation of he... Read More about FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy.

The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait (2019)
Journal Article
Bishop, P. J., Scofield, R. P., & Hocknull, S. A. (2019). The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait. https://doi.org/10.1080/03115518.2019.1594380

The extinct, flightless moa of New Zealand included some of the largest birds to have existed and possessed many distinguishing pelvic and hindlimb osteological features. These features may have influenced stance and gait in moa compared with extant... Read More about The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait.