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Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling (2016)
Journal Article
Gill, R. M. S., Mehra, V., Milford, E., & Dhoot, G. K. (2016). Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling. Histochemistry and Cell Biology, 146, 431-144. https://doi.org/10.1007/s00418-016-1454-3

The relative roles of SULF1 and SULF2 enzymes in tumour growth are controversial, but short SULF1/SULF2 splice variants predominate in human mammary tumours despite their non-detectable levels in normal mammary tissue. Compared with the normal, the l... Read More about Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.

Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle (2016)
Journal Article
Adams, H. A., Sonstegard, T. S., VanRaden, P. M., Null, D. J., Van Tassell, C. P., Larkin, D. M., & Lewin, H. A. (2016). Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle. Journal of Dairy Science, 99(8), 6693-6701. https://doi.org/10.3168/jds.2015-10517

Morphomechanical Innovation Drives Explosive Seed Dispersal (2016)
Journal Article
Hofhuis, H., Moulton, D., Lessinnes, T., Routier-Kierzkowska, A. L., Bomphrey, R. J., Mosca, G., …Hay, A. (2016). Morphomechanical Innovation Drives Explosive Seed Dispersal. Cell, 166, 222-233. https://doi.org/10.1016/j.cell.2016.05.002

How mechanical and biological processes are coordinated across cells, tissues, and organs to produce complex traits is a key question in biology. Cardamine hirsuta, a relative of Arabidopsis thaliana, uses an explosive mechanism to disperse its seeds... Read More about Morphomechanical Innovation Drives Explosive Seed Dispersal.

E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models (2016)
Journal Article
Staines, K. A., Prideaux, M., Allen, S. P., Buttle, D. J., Pitsillides, A. A., & Farquharson, C. (2016). E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models. Journal of Cellular Physiology, 231(6), 1392-1404. https://doi.org/10.1002/jcp.25282

The transmembrane glycoprotein E11 is considered critical in early osteoblast–osteocyte transitions (osteocytogenesis), however its function and regulatory mechanisms are still unknown. Using the late osteoblast MLO-A5 cell line we reveal increased E... Read More about E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models.

Inferring muscle functional roles of the ostrich pelvic limb during walking and running using computer optimization (2016)
Journal Article
Rankin, J. W., Rubenson, J., & Hutchinson, J. R. (2016). Inferring muscle functional roles of the ostrich pelvic limb during walking and running using computer optimization. https://doi.org/10.1098/rsif.2016.0035

Owing to their cursorial background, ostriches (Struthio camelus) walk and run with high metabolic economy, can reach very fast running speeds and quickly execute cutting manoeuvres. These capabilities are believed to be a result of their ability to... Read More about Inferring muscle functional roles of the ostrich pelvic limb during walking and running using computer optimization.