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Occipital foramina development involves localised regulation of mesenchyme proliferation and is independent of apoptosis (2015)
Journal Article
Akbareian, S. E., Pitsillides, A. A., Macharia, R. G., & McGonnell, I. M. (2015). Occipital foramina development involves localised regulation of mesenchyme proliferation and is independent of apoptosis. Journal of Anatomy, 226(6), 560-574. https://doi.org/10.1111/joa.12304

Cranial foramina are holes within the skull, formed during development, allowing entry and exit of blood vessels and nerves. Once formed they must remain open, due to the vital structures they contain, i.e. optic nerves, jugular vein, carotid artery,... Read More about Occipital foramina development involves localised regulation of mesenchyme proliferation and is independent of apoptosis.

A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum (2015)
Journal Article
Krishna, R., Xia, D., Sanderson, S., Shanmugasundram, A., Vermont, S., Bernal, A., …Jones, A. R. (2015). A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum. Proteomics, 15(15), 261828. https://doi.org/10.1002/pmic.201400553

Proteomics data can supplement genome annotation efforts, for example being used to confirm gene models or correct gene annotation errors. Here, we present a large‐scale proteogenomics study of two important apicomplexan pathogens: Toxoplasma gondii... Read More about A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum.

Randomized placebo-controlled clinical trial of a new chewable formulation of amlodipine for the treatment of hypertension in client-owned cats (2015)
Journal Article
Huhtinen, M., Derre, G., Renoldi, H. J., Rinkinen, M., Adler, K., Aspegren, J., …Elliott, J. (2015). Randomized placebo-controlled clinical trial of a new chewable formulation of amlodipine for the treatment of hypertension in client-owned cats. Journal of Veterinary Internal Medicine, 29(3), 786-793. https://doi.org/10.1111/jvim.12589

Nuclear receptors in vascular biology (2015)
Journal Article
Bishop-Bailey, D. (2015). Nuclear receptors in vascular biology. Current Atherosclerosis Reports, 17(5), https://doi.org/10.1007/s11883-015-0507-8

Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics. In response to these diverse but critica... Read More about Nuclear receptors in vascular biology.

Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis (2015)
Journal Article
Zolfaghari, P. S., Carré, J. E., Parker, N., Curtin, N. A., Duchen, M. R., & Singer, M. (2015). Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis. https://doi.org/10.1152/ajpendo.00562.2014

Muscle dysfunction is a common feature of severe sepsis and multi-organ failure. Recent evidence implicates bioenergetic dysfunction and oxidative damage as important underlying pathophysiological mechanisms. Increased abundance of uncoupling protein... Read More about Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis.

Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise (2015)
Journal Article
Spiesz, E. M., Thorpe, C. T., Chaudhry, S., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. (2015). Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise. Journal of Orthopaedic Research, 33(6), 889-97. https://doi.org/10.1002/jor.22879

The role of inflammation in tendon injury is uncertain and a topic of current interest. In vitro studies of tendon accelerated overload damage can serve as a valuable source of information on the early stages of tendinopathy. Viable fascicle bundles... Read More about Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise.

Long-term high fat feeding of rats results in increased numbers of circulating microvesicles with pro-inflammatory effects on endothelial cells (2015)
Journal Article
Heinrich, L. F., Andersen, D. K., Cleasby, M. E., & Lawson, C. (2015). Long-term high fat feeding of rats results in increased numbers of circulating microvesicles with pro-inflammatory effects on endothelial cells. British Journal of Nutrition, 113(11), 1704-11. https://doi.org/10.1017/S0007114515001117

Obesity and type 2 diabetes lead to dramatically increased risks of atherosclerosis and CHD. Multiple mechanisms converge to promote atherosclerosis by increasing endothelial oxidative stress and up-regulating expression of pro-inflammatory molecules... Read More about Long-term high fat feeding of rats results in increased numbers of circulating microvesicles with pro-inflammatory effects on endothelial cells.

FINITE ELEMENT ANALYSIS OF TISSUES WRAPPING AROUND THE KNEE JOINT OF OSTRICHES (STRUTHIO CAMELUS) (2015)
Journal Article
Chadwick, K. P., Allen, V. R., & Hutchinson, J. R. (2015). FINITE ELEMENT ANALYSIS OF TISSUES WRAPPING AROUND THE KNEE JOINT OF OSTRICHES (STRUTHIO CAMELUS). FASEB Journal, 29(1),

Mechanical stimulation is accepted to play some role in the development of sesamoid bones, however with great variability in occurrence, it is not yet clear how significant this role is and what specific loading environment fosters or hinders growth.... Read More about FINITE ELEMENT ANALYSIS OF TISSUES WRAPPING AROUND THE KNEE JOINT OF OSTRICHES (STRUTHIO CAMELUS).