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Nuclear receptors in vascular biology

Bishop-Bailey, D


D Bishop-Bailey


Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics. In response to these diverse but critically important mediators, nuclear receptors regulate the homeostatic control of lipids, carbohydrate, cholesterol, and xenobiotic drug metabolism, inflammation, cell differentiation and development, including vascular development. The nuclear receptor family is one of the most important groups of signaling molecules in the body and as such represent some of the most important established and emerging clinical and therapeutic targets. This review will highlight some of the recent trends in nuclear receptor biology related to vascular biology.


Bishop-Bailey, D. (2015). Nuclear receptors in vascular biology. Current Atherosclerosis Reports, 17(5),

Journal Article Type Review
Acceptance Date Mar 1, 2015
Publication Date May 1, 2015
Deposit Date Oct 20, 2015
Publicly Available Date Feb 12, 2019
Journal Current Atherosclerosis Reports
Print ISSN 1523-3804
Publisher Springer
Peer Reviewed Peer Reviewed
Volume 17
Issue 5
Public URL


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