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Big cat, small cat: Reconstructing body size evolution in living and extinct Felidae
Journal Article
Cuff, A. R., Randau, M., Head, J., Hutchinson, J. R., Pierce, S. E., & Goswami, A. (in press). Big cat, small cat: Reconstructing body size evolution in living and extinct Felidae. Journal of Evolutionary Biology, 28(8), 1516-1525. https://doi.org/10.1111/jeb.12671

The evolution of body mass is a fundamental topic in evolutionary biology, because it is closely linked to manifold life history and ecological traits and is readily estimable for many extinct taxa. In this study, we examine patterns of body mass evo... Read More about Big cat, small cat: Reconstructing body size evolution in living and extinct Felidae.

MMP and TIMP temporal gene expression during osteocytogenesis
Journal Article
Prideaux, M., Staines, K. A., Jones, E. R., Riley, G. P., Pitsillides, A. A., & Farquharson, C. (in press). MMP and TIMP temporal gene expression during osteocytogenesis. Gene Expression Patterns, 18(1-2), 29-36. https://doi.org/10.1016/j.gep.2015.04.004

Osteocytes within bone differentiate from osteoblast precursors which reside in a mineralised extracellular matrix (ECM). Fully differentiated osteocytes are critical for bone development and function but the factors that regulate this differentiatio... Read More about MMP and TIMP temporal gene expression during osteocytogenesis.

A Missense Mutation in KCTD17 Causes Autosomal Dominant Myoclonus-Dystonia
Journal Article
Mencacci, N. E., Rubio-Agusti, I., Zdebik, A., Asmus, F., Ludtmann, M. H. R., Ryten, M., …Wood, N. W. (in press). A Missense Mutation in KCTD17 Causes Autosomal Dominant Myoclonus-Dystonia. American Journal of Human Genetics, 96(6), 938-47. https://doi.org/10.1016/j.ajhg.2015.04.008

Myoclonus-dystonia (M-D) is a rare movement disorder characterized by a combination of non-epileptic myoclonic jerks and dystonia. SGCE mutations represent a major cause for familial M-D being responsible for 30%–50% of cases. After excluding SGCE mu... Read More about A Missense Mutation in KCTD17 Causes Autosomal Dominant Myoclonus-Dystonia.