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Outputs (34)

Spontaneous dog osteoarthritis — a One Medicine vision (2019)
Journal Article
Meeson, R. L., Todhunter, R. J., Blunn, G., Nuki, G., & Pitsillides, A. A. (2019). Spontaneous dog osteoarthritis — a One Medicine vision. Nature Reviews Rheumatology, 15(5), 273-287. https://doi.org/10.1038/s41584-019-0202-1

Osteoarthritis (OA) is a global disease that, despite extensive research, has limited treatment options. Pet dogs share both an environment and lifestyle attributes with their owners, and a growing awareness is developing in the public and among rese... Read More about Spontaneous dog osteoarthritis — a One Medicine vision.

CXCR4 Antagonism to Treat Delayed Fracture Healing (2019)
Journal Article
Meeson, R. L., Sanghani, A., Coathup, M., & Blunn, G. (2019). CXCR4 Antagonism to Treat Delayed Fracture Healing. https://doi.org/10.1089/ten.TEA.2018.0265

A significant number of fractures develop non-union. Stem cell homing is regulated through SDF-1 and its receptor CXCR4. Stem/progenitor cell populations can be endogenously mobilised by administering growth factors with a pharmacological antagonist... Read More about CXCR4 Antagonism to Treat Delayed Fracture Healing.

Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures (2018)
Journal Article
Osagie-Clouard, L., Kaufmann, J., Blunn, G., Coathup, M., Pendegrass, C., Meeson, R. L., …Moazen, M. (2018). Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures. Journal of Orthopaedic Research, https://doi.org/10.1002/jor.24034

The use of external fixators allows for the direct investigation of newly formed interfragmentary bone, and the radiographic evaluation of the fracture. We validated the results of a finite element model with the in vitro stiffness' of two widely use... Read More about Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures.