Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures

Osagie-Clouard, L; Kaufmann, J; Blunn, G; Coathup, M; Pendegrass, C; Meeson, R L; Briggs, T; Moazen, M

Abstract

The use of external fixators allows for the direct investigation of newly formed interfragmentary bone, and the radiographic evaluation of the fracture. We validated the results of a finite element model with the in vitro stiffness' of two widely used external fixator devices used for in vivo analysis of fracture healing in rat femoral fractures with differing construction (Ti alloy ExFix1 and PEEK ExFix2). Rat femoral fracture fixation was modelled using two external fixators. For both constructs an osteotomy of 2.75 mm was used, and offset maintained at 5 mm. Tufnol, served as standardized substitutes for rat femora. Constructs were loaded under axial compression and torsion. Overall axial and torsional stiffness were compared between the in vitro models and FE results. FE models were also used to compare the fracture movement and overall pattern of von Mises stress across the external fixators. In vitro axial stiffness of ExFix1 was 29.26 N/mm ± 3.83 compared to ExFix2 6.31 N/mm ± 0.67 (p* 

Citation

Osagie-Clouard, L., Kaufmann, J., Blunn, G., Coathup, M., Pendegrass, C., Meeson, R. L., …Moazen, M. (2018). Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures. Journal of Orthopaedic Research, https://doi.org/10.1002/jor.24034

• Journal Article Type: Article
• Acceptance Date: May 1, 2018
• Publication Date: May 4, 2018
• Deposit Date: Jul 12, 2018
• Publicly Available Date: May 8, 2019
• Journal: JOURNAL OF ORTHOPAEDIC RESEARCH
• Print ISSN: 0736-0266
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1002/jor.24034
• Public URL: https://rvc-repository.worktribe.com/output/1387383