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Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures

Osagie-Clouard, L; Kaufmann, J; Blunn, G; Coathup, M; Pendegrass, C; Meeson, R L; Briggs, T; Moazen, M


L Osagie-Clouard

J Kaufmann

G Blunn

M Coathup

C Pendegrass

R L Meeson

T Briggs

M Moazen


The use of external fixators allows for the direct investigation of newly formed interfragmentary bone, and the radiographic evaluation of the fracture. We validated the results of a finite element model with the in vitro stiffness' of two widely used external fixator devices used for in vivo analysis of fracture healing in rat femoral fractures with differing construction (Ti alloy ExFix1 and PEEK ExFix2). Rat femoral fracture fixation was modelled using two external fixators. For both constructs an osteotomy of 2.75 mm was used, and offset maintained at 5 mm. Tufnol, served as standardized substitutes for rat femora. Constructs were loaded under axial compression and torsion. Overall axial and torsional stiffness were compared between the in vitro models and FE results. FE models were also used to compare the fracture movement and overall pattern of von Mises stress across the external fixators. In vitro axial stiffness of ExFix1 was 29.26 N/mm ± 3.83 compared to ExFix2 6.31 N/mm ± 0.67 (p* 


Osagie-Clouard, L., Kaufmann, J., Blunn, G., Coathup, M., Pendegrass, C., Meeson, R. L., …Moazen, M. (2018). Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures. Journal of Orthopaedic Research,

Journal Article Type Article
Acceptance Date May 1, 2018
Publication Date May 4, 2018
Deposit Date Jul 12, 2018
Publicly Available Date May 8, 2019
Print ISSN 0736-0266
Publisher Wiley
Peer Reviewed Peer Reviewed
Public URL


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