Skip to main content

Research Repository

Advanced Search

Outputs (3013)

Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia (2016)
Journal Article
Sanchis-Mora, S., Pelligand, L., Thomas, C. L., Volk, H. A., Abeyesinghe, S. M., Brodbelt, D. C., …O'Neill, D. G. (2016). Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia. Veterinary Record, 179(17), 436. https://doi.org/10.1136/vr.103651

Chiari-like malformation/syringomyelia (CM/SM) in dogs describes a developmental disorder that can cause pain and reduced quality of life. This retrospective study aimed to report the period prevalence, clinical signs and risk factors for diagnosis o... Read More about Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia.

Single Nucleotide Polymorphisms in Major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs (2016)
Journal Article
Peiravan, A., Allenspach, K., Boag, A. M., Soutter, F., Holder, A. L., Catchpole, B., …Procoli, F. (2016). Single Nucleotide Polymorphisms in Major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs. Veterinary Immunology and Immunopathology, 182, 101-105. https://doi.org/10.1016/j.vetimm.2016.10.012

Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats (2016)
Journal Article
Pelligand, L., Soubret, A., King, J. N., Elliott, J., & Mochel, J. P. (2016). Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats. https://doi.org/10.1002/psp4.12141

The objective of this study was to model the pharmacokinetics (PKs) of robenacoxib in cats using a nonlinear mixed‐effects (NLME) approach, leveraging all available information collected from cats receiving robenacoxib s.c. and/or i.v.: 47 densely sa... Read More about Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats.

Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries (2016)
Journal Article
Garvican, E. R., Salavati, M., Smith, R. K. W., & Dudhia, J. (2016). Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries. Connective Tissue Research, 58(5), 438-446. https://doi.org/10.1080/03008207.2016.1245726

Aim: The purpose of this study was to investigate the effect of normal synovial fluid (SF) on exposed endogenous tendon-derived cells (TDC) and engrafted mesenchymal stem cells (MSCs) within the tendon extracellular matrix. Methods: Explants from eq... Read More about Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries.

Method specific calibration corrects for DNA extraction method effects on relative telomere length measurements by quantitative PCR (2016)
Journal Article
Seeker, L. A., Holland, R., Underwood, S., Fairlie, J., Psifidi, A., Ilska, J. J., …Nussey, D. H. (2016). Method specific calibration corrects for DNA extraction method effects on relative telomere length measurements by quantitative PCR. PLoS ONE, https://doi.org/10.1371/journal.pone.0164046

Telomere length (TL) is increasingly being used as a biomarker in epidemiological, biomedical and ecological studies. A wide range of DNA extraction techniques have been used in telomere experiments and recent quantitative PCR (qPCR) based studies su... Read More about Method specific calibration corrects for DNA extraction method effects on relative telomere length measurements by quantitative PCR.

Comparison of clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with acute non compressive nucleus pulposus extrusion (2016)
Journal Article
Fenn, J. T., Drees, R., Volk, H. A., & De Decker, S. (2016). Comparison of clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with acute non compressive nucleus pulposus extrusion. Journal of the American Veterinary Medical Association, 249(7), 767-775. https://doi.org/10.2460/javma.249.7.767

Genome-wide association studies of immune, disease and productivity traits in indigenous chicken ecotypes (2016)
Journal Article
Psifidi, A., Banos, G., Matika, O., Desta, T. T., Bettridge, J., Hume, D. A., …Kaiser, P. (2016). Genome-wide association studies of immune, disease and productivity traits in indigenous chicken ecotypes. Genetics Selection Evolution, 48(74), https://doi.org/10.1186/s12711-016-0252-7

The majority of chickens in sub-Saharan Africa are indigenous ecotypes, well adapted to the local environment and raised in scavenging production systems. Although they are generally resilient to disease challenge, routine vaccination and biosecurity... Read More about Genome-wide association studies of immune, disease and productivity traits in indigenous chicken ecotypes.