Skip to main content

Research Repository

Advanced Search

Outputs (159)

Population Pharmacokinetics and Pharmacodynamics Modeling of Torasemide and Furosemide After Oral Repeated Administration in Healthy Dogs (2020)
Journal Article
Pelligand, L., Guillot, E., Geneteau, A., Guyonnet, J., Magnier, R., Elliott, J., …Jacobs, M. (2020). Population Pharmacokinetics and Pharmacodynamics Modeling of Torasemide and Furosemide After Oral Repeated Administration in Healthy Dogs. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00151

Torasemide is a loop diuretic licensed in dogs for cardiogenic pulmonary oedema. The aim of this pharmacokinetic-pharmacodynamic (PK/PD) study was to define an optimally effective dosage regimen based on preclinical data. In a first study, 5 dogs rec... Read More about Population Pharmacokinetics and Pharmacodynamics Modeling of Torasemide and Furosemide After Oral Repeated Administration in Healthy Dogs.

Characterisation of Crandell-Rees Feline Kidney (CRFK) cells as mesenchymal in phenotype (2019)
Journal Article
Lawson, J. S., Syme, H. M., Wheeler-Jones, C. P. D., & Elliott, J. (2019). Characterisation of Crandell-Rees Feline Kidney (CRFK) cells as mesenchymal in phenotype. Research in Veterinary Science, 127, 99-102. https://doi.org/10.1016/j.rvsc.2019.10.012

The Crandell-Rees Feline Kidney Cell (CRFK) is an immortalised cell line derived from the feline kidney that is utilised for the growth of certain vaccinal viruses. Confusion exists as to whether CRFK are epithelial or mesenchymal in phenotype. The a... Read More about Characterisation of Crandell-Rees Feline Kidney (CRFK) cells as mesenchymal in phenotype.

Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs (2019)
Journal Article
Pelander, L., Brunchault, V., Buffin-Meyer, B., Klein, J., Breuil, B., Zürbig, P., …Ljungvall, I. (2019). Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs. https://doi.org/10.1016/j.tvjl.2019.05.010

Chronic kidney disease (CKD) is clinically important in canine medicine. Current diagnostic tools lack sensitivity for detection of subclinical CKD. The aim of the present study was to evaluate urinary peptidome analysis for diagnosis of CKD in dogs.... Read More about Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs.

Physics of Animal Health: On the mechano-biology of hoof growth and form (2019)
Journal Article
Al-Agele, R., Paul, E., Taylor, S., Watson, C., Sturrock, C., Drakopoulos, M., …Rauch, C. (2019). Physics of Animal Health: On the mechano-biology of hoof growth and form. https://doi.org/10.1098/rsif.2019.0214

Global inequalities in economic access and agriculture productivity imply that a large number of developing countries rely on working equids for transport/agriculture/mining. Therefore, the understanding of hoof conditions/shape variations affecting... Read More about Physics of Animal Health: On the mechano-biology of hoof growth and form.

Comparison of the diagnostic value of symmetric dimethylarginine, cystatin C, and creatinine for detection of decreased glomerular filtration rate in dogs (2019)
Journal Article
Pelander, L., Häggström, J., Larsson, A., Syme, H. M., Elliott, J., Heiene, R., & Ljungvall, I. (2019). Comparison of the diagnostic value of symmetric dimethylarginine, cystatin C, and creatinine for detection of decreased glomerular filtration rate in dogs. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15445