Pathobiology and Population Sciences

Structural characterisation of Toll-like receptor 1 (TLR1) and Toll-like receptor 6 (TLR6) in elephant and harbor seals
Journal Article
Woodman, S., Gibson, A. J., Garcia, A. R., Contreras, G. S., Rossen, J. W., Werling, D., & Offord, V. (in press). Structural characterisation of Toll-like receptor 1 (TLR1) and Toll-like receptor 6 (TLR6) in elephant and harbor seals. Veterinary Immunology and Immunopathology, 169, 10-4. https://doi.org/10.1016/j.vetimm.2015.11.006

Effect of the synthetic Toll-like receptor ligands LPS, Pam3CSK4, HKLM and FSL-1 in the function of bovine polymorphonuclear neutrophils
Journal Article
Conejeros, I., Gibson, A. J., Werling, D., Munoz-Caro, T., Hermosilla, C., Taubert, A., & Burgos, R. A. (in press). Effect of the synthetic Toll-like receptor ligands LPS, Pam3CSK4, HKLM and FSL-1 in the function of bovine polymorphonuclear neutrophils. Developmental and Comparative Immunology, 52(2), 215-225. https://doi.org/10.1016/j.dci.2015.05.012

Toll-like receptors (TLR) are a family of pattern recognition receptors that sense microbial associated molecular patterns (MAMP) such as microbial membrane components and nucleic acids of bacterial origin. Polymorphonuclear neutrophils (PMN) are the... Read More about Effect of the synthetic Toll-like receptor ligands LPS, Pam3CSK4, HKLM and FSL-1 in the function of bovine polymorphonuclear neutrophils.

Bovine macrophages sense Escherichia coli Shiga toxin 1
Journal Article
Menge, C., Loos, D., Bridger, P. S., Barth, S., Werling, D., & Baljier, G. (in press). Bovine macrophages sense Escherichia coli Shiga toxin 1. Innate Immunity, 21(6), 655-664. https://doi.org/10.1177/1753425915581215

Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy
Journal Article
Schmitz, S., Werling, D., & Allenspach, K. (in press). Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy. PLoS ONE, 10(3), e0120779. https://doi.org/10.1371/journal.pone.0120779

Inflammasomes coordinate the maturation of IL-1β and IL-18 in response to danger signals. They are vital for maintenance of intestinal homeostasis and have been linked to chronic intestinal inflammation in humans. Probiotics have been advocated as tr... Read More about Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy.

Lack of Correlation between Mucosal Immunoglobulin A-positive Plasma Cell Numbers and TLR5 Genotypes in German Shepherd Dogs with Idiopathic Chronic Enteropathy
Journal Article
Lee, A., Kathrani, A., Priestnall, S. L., Smith, K. C., Werling, D., & Allenspach, K. (in press). Lack of Correlation between Mucosal Immunoglobulin A-positive Plasma Cell Numbers and TLR5 Genotypes in German Shepherd Dogs with Idiopathic Chronic Enteropathy. Journal of Comparative Pathology, 152(2-3), 201-5. https://doi.org/10.1016/j.jcpa.2015.01.002

Vaccination of calves with yeast- and bacterial-expressed paramyosin from the bovine lungworm Dictyocaulus viviparus
Journal Article
Joekel, D., Hinse, P., Raulf, M. K., Schicht, S., Baumer, W., Werling, D., …Strube, C. Vaccination of calves with yeast- and bacterial-expressed paramyosin from the bovine lungworm Dictyocaulus viviparus. Parasite Immunology, 37(12), 614-623. https://doi.org/10.1111/pim.12280

Outputs (147)