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Outputs (173)

Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting (2016)
Journal Article
Bergquist, H., Rocha, C. S., Alvarez-Asencio, R., Nguyen, C. H., Rutland, M. W., Smith, C. I., …Zain, R. (2016). Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting. PLoS ONE, 15(11), e0165788. https://doi.org/10.1371/journal.pone.0165788

Expansion of (GAA)n repeats in the first intron of the Frataxin gene is associated with reduced mRNA and protein levels and the development of Friedreich’s ataxia. (GAA)n expansions form non-canonical structures, including intramolecular triplex (H-D... Read More about Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting.

An Age-Associated Decline in Thymic Output Differs in Dog Breeds According to Their Longevity (2016)
Journal Article
Holder, A., Mella, S., Palmer, D. B., Aspinall, R., & Catchpole, B. (2016). An Age-Associated Decline in Thymic Output Differs in Dog Breeds According to Their Longevity. PLoS ONE, 11, e0165968. https://doi.org/10.1371/journal.pone.0165968

The age associated decline in immune function is preceded in mammals by a reduction in thymic output. Furthermore, there is increasing evidence of a link between immune competence and lifespan. One approach to determining thymic output is to quantify... Read More about An Age-Associated Decline in Thymic Output Differs in Dog Breeds According to Their Longevity.

Methods and Processes of Developing the Strengthening the Reporting of Observational Studies in Epidemiology – Veterinary (STROBE-Vet) Statement (2016)
Journal Article
Sargeant, J. M., O'Connor, A. M., Dohoo, I. R., Erb, H. N., Cevallos, M., Egger, M., …Ward, M. P. (2016). Methods and Processes of Developing the Strengthening the Reporting of Observational Studies in Epidemiology – Veterinary (STROBE-Vet) Statement. Journal of Veterinary Internal Medicine, 30, 1887-1895. https://doi.org/10.1111/jvim.14574

Explanation and Elaboration Document for the STROBE-Vet Statement: Strengthening the Reporting of Observational Studies in Epidemiology—Veterinary Extension (2016)
Journal Article
O'Connor, A. M., Sargeant, J. M., Dohoo, I. R., Erb, H. N., Cevallos, M., Egger, M., …Ward, M. P. (2016). Explanation and Elaboration Document for the STROBE-Vet Statement: Strengthening the Reporting of Observational Studies in Epidemiology—Veterinary Extension. Journal of Veterinary Internal Medicine, 30, 1896-1928. https://doi.org/10.1111/jvim.14592