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Outputs (8)

Decision tree machine learning applied to bovine tuberculosis risk factors to aid disease control decision making (2019)
Journal Article
Romero, M. P., Chang, Y. M., Brunton, L. A., Parry, J., Prosser, A., Upton, P., …Drewe, J. A. (2019). Decision tree machine learning applied to bovine tuberculosis risk factors to aid disease control decision making. Preventive Veterinary Medicine, https://doi.org/10.1016/j.prevetmed.2019.104860

Identifying and understanding the risk factors for endemic bovine tuberculosis (TB) in cattle herds is critical for the control of this disease. Exploratory machine learning techniques can uncover complex non-linear relationships and interactions wit... Read More about Decision tree machine learning applied to bovine tuberculosis risk factors to aid disease control decision making.

Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice (2019)
Journal Article
Ying Wu, , Chang, Y. M., Stell, A. J., Priestnall, S. L., Sharma, E., Goulart, M. R., …Garden, O. A. (2019). Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice. https://doi.org/10.1038/s41598-019-50065-8

Regulatory T cells (Tregs) are a double-edged regulator of the immune system. Aberrations of Tregs correlate with pathogenesis of inflammatory, autoimmune and neoplastic disorders. Phenotypically and functionally distinct subsets of Tregs have been i... Read More about Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice.

Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows (2019)
Journal Article
Tombacz, K., Peters, L. M., Chang, Y. M., Steele, M., Werling, D., & Gibson, A. J. (2019). Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows. Journal of Dairy Science, 102(10), 9389-9395. https://doi.org/10.3168/jds.2019-16563

In periparturient dairy cows, immune suppression, resulting in decreased neutrophil numbers and function, leads to increased susceptibility to postpartum conditions such as mastitis, retained placenta, and metritis. Administration of polyethylene gly... Read More about Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows.

Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial (2019)
Journal Article
Sanchis-Mora, S., Chang, Y. M., Abeyesinghe, S. M., Fisher, A., Upton, N., Volk, H. A., & Pelligand, L. (2019). Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial. https://doi.org/10.1016/j.tvjl.2019.06.006

Pregabalin is the first-line treatment for neuropathic pain (NeP) in humans. Dogs with Chiari-like malformation and syringomyelia (CM/SM) associated with NeP could benefit from pregabalin. The aim of this study was to evaluate the efficacy of pregaba... Read More about Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial.

Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome (2019)
Journal Article
Pittaway, R., Dobromylskyj, M. J., Erles, K., Pittaway, C. E., Suárez-Bonnet, A., Chang, Y. M., & Priestnall, S. L. (2019). Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome. Veterinary Pathology, 56(6), 868-877. https://doi.org/10.1177/0300985819854435

Nonocular melanocytic neoplasia is considered uncommon in cats yet is routinely encountered in diagnostic pathology and recognized to exhibit a wide variation in biological behavior. Accurate prediction of clinical outcomes is challenging with no wid... Read More about Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome.

Chronic kidney disease in cats attending primary care practice in the UK: a VetCompassTM study (2019)
Journal Article
Conroy, M. C., Brodbelt, D. C., O'Neill, D. G., Chang, Y. M., & Elliott, J. (2019). Chronic kidney disease in cats attending primary care practice in the UK: a VetCompassTM study. Veterinary Record, 184(17), https://doi.org/10.1136/vr.105100

Chronic kidney disease (CKD) is a frequent diagnosis in cats attending primary care practice and the most frequent cause of death in cats aged over five years, yet there is limited published research for CKD in cats attending primary care practice. T... Read More about Chronic kidney disease in cats attending primary care practice in the UK: a VetCompassTM study.

Multivariable analysis to determine risk factors associated with early pregnancy loss in thoroughbred broodmares (2019)
Journal Article
De Mestre, A. M., Rose, V. B., Chang, Y. M., Wathes, D. C., & Verheyen, K. L. P. (2019). Multivariable analysis to determine risk factors associated with early pregnancy loss in thoroughbred broodmares. Theriogenology, 124, 18-23. https://doi.org/10.1016/j.theriogenology.2018.10.008

Early pregnancy loss (EPL) between days 15–65 after breeding has been shown to occur in 7.9% of equine pregnancies with substantial economical, welfare and safety implications. Whilst maternal age has been recognised as an important risk factor in re... Read More about Multivariable analysis to determine risk factors associated with early pregnancy loss in thoroughbred broodmares.