Outputs (150)

Escape of TLR5 Recognition by Leptospira spp.: A Rationale for Atypical Endoflagella (2020)
Journal Article
Holzapfel, M., Bonhomme, D., Cagliero, J., Vernel-Pauillac, F., Fanton d’Andon, M., Bortolussi, S., …Werts, C. (2020). Escape of TLR5 Recognition by Leptospira spp.: A Rationale for Atypical Endoflagella. Frontiers in Immunology, 11, https://doi.org/10.3389/fimmu.2020.02007

Leptospira (L.) interrogans are invasive bacteria responsible for leptospirosis, a worldwide zoonosis. They possess two periplasmic endoflagellae that allow their motility. L. interrogans are stealth pathogens that escape the innate immune recognitio... Read More about Escape of TLR5 Recognition by Leptospira spp.: A Rationale for Atypical Endoflagella.

Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis (2020)
Journal Article
Holder, A., Garty, R., Elder, C., Mesnard, P., Laquerbe, C., Bartens, M., …Werling, D. (2020). Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis. Frontiers in Microbiology, 11, https://doi.org/10.3389/fmicb.2020.01420

Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is a chronic zoonotic disease where host genetics is thought to contribute to susceptibility or resistance. One of the genes implicated is the SLC11A1 gene, that encodes for the natural resist... Read More about Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis.

A Genome-Wide Association Study for Calving Interval in Holstein Dairy Cows Using Weighted Single-Step Genomic BLUP Approach. (2020)
Journal Article
Atashi, H., Salavati, M., De Koster, J., Crowe, M., Opsomer, G., Hostens, M., & Werling, D. (2020). A Genome-Wide Association Study for Calving Interval in Holstein Dairy Cows Using Weighted Single-Step Genomic BLUP Approach. Animals, 10(3),

The aim of the present study was to identify genomic region(s) associated with the length of the calving interval in primiparous (n = 6866) and multiparous (n = 5071) Holstein cows. The single nucleotide polymorphism (SNP) solutions were estimated us... Read More about A Genome-Wide Association Study for Calving Interval in Holstein Dairy Cows Using Weighted Single-Step Genomic BLUP Approach..

Poultry Coccidiosis: Design and Interpretation of Vaccine Studies (2020)
Journal Article
Soutter, F., Werling, D., Tomley, F. M., & Blake, D. P. (2020). Poultry Coccidiosis: Design and Interpretation of Vaccine Studies. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00101

Eimeria infection impacts upon chicken welfare and economic productivity of the poultry sector. Live coccidiosis vaccines for chickens have been available for almost 70 years, but the requirement to formulate blends of oocysts from multiple Eimeria s... Read More about Poultry Coccidiosis: Design and Interpretation of Vaccine Studies.

Mammalian lectin arrays for screening host-microbe interactions (2020)
Journal Article
Jégouzo, S. A. F., Nelson, C., Hardwick, T., Wong, S. T. A., Lau, N. K. K., Neoh, G. K. E., …Drickamer, K. (2020). Mammalian lectin arrays for screening host-microbe interactions. Journal of Biological Chemistry, 295(14), 4541-4555. https://doi.org/10.1074/jbc.RA120.012783

Many members of the C-type lectin family of glycan-binding receptors have been ascribed roles in the recognition of microorganisms and serve as key receptors in the innate immune response to pathogens. Other mammalian receptors have become targets th... Read More about Mammalian lectin arrays for screening host-microbe interactions.

Genome-wide association for milk production and lactation curve parameters in Holstein dairy cows. (2019)
Journal Article
Atashi, H., Salavati, M., De Koster, J., Ehrlich, J., Crowe, M., Opsomer, G., …Werling, D. (2019). Genome-wide association for milk production and lactation curve parameters in Holstein dairy cows. Journal of Animal Breeding and Genetics, 137(3), 292-304. https://doi.org/10.1111/jbg.12442

The aim of this study was to identify genomic regions associated with 305-day milk yield and lactation curve parameters on primiparous (n = 9,910) and multiparous (n = 11,158) Holstein cows. The SNP solutions were estimated using a weighted single-st... Read More about Genome-wide association for milk production and lactation curve parameters in Holstein dairy cows..

CD23 is a glycan-binding receptor in some mammalian species (2019)
Journal Article
Jégouzo, S. A. F., Feinberg, H., Morrison, A., Holder, A., May, A., Huang, Z., …Taylor, M. E. (2019). CD23 is a glycan-binding receptor in some mammalian species. Journal of Biological Chemistry, https://doi.org/10.1074/jbc.RA119.010572

CD23, the low affinity IgE receptor found on B lymphocytes and other cells, contains a C-terminal lectin-like domain that resembles C-type carbohydrate-recognition domains (CRDs) found in many glycan-binding receptors. In most mammalian species, the... Read More about CD23 is a glycan-binding receptor in some mammalian species.

Administration of a Synbiotic Containing Enterococcus faecium Does Not Significantly Alter Fecal Microbiota Richness or Diversity in Dogs With and Without Food-Responsive Chronic Enteropathy (2019)
Journal Article
Pilla, R., Guard, B. C., Steiner, J. M., Gaschen, F. P., Olson, E., Werling, D., …Suchodolski, J. S. (2019). Administration of a Synbiotic Containing Enterococcus faecium Does Not Significantly Alter Fecal Microbiota Richness or Diversity in Dogs With and Without Food-Responsive Chronic Enteropathy. Frontiers in Veterinary Science, https://doi.org/10.3389/fvets.2019.00277

Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows (2019)
Journal Article
Tombacz, K., Peters, L. M., Chang, Y. M., Steele, M., Werling, D., & Gibson, A. J. (2019). Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows. Journal of Dairy Science, 102(10), 9389-9395. https://doi.org/10.3168/jds.2019-16563

In periparturient dairy cows, immune suppression, resulting in decreased neutrophil numbers and function, leads to increased susceptibility to postpartum conditions such as mastitis, retained placenta, and metritis. Administration of polyethylene gly... Read More about Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows.

Differential Responses of Bovine Monocyte-Derived Macrophages to Infection by Neospora caninum Isolates of High and Low Virulence (2019)
Journal Article
García-Sánchez, M., Jiménez-Pelayo, L., Horcajo, P., Regidor-Cerrillo, J., Ólafsson, E. B., Bhandage, A. K., …Collantes-Fernández, E. (2019). Differential Responses of Bovine Monocyte-Derived Macrophages to Infection by Neospora caninum Isolates of High and Low Virulence. Frontiers in Immunology, 10(915), https://doi.org/10.3389/fimmu.2019.00915

Neospora caninum, a protozoan parasite closely related to Toxoplasma gondii, represents one of the main causes of abortion in cattle. Macrophages (MØs) are mediators of the innate immune response against infection and likely one of the first cells en... Read More about Differential Responses of Bovine Monocyte-Derived Macrophages to Infection by Neospora caninum Isolates of High and Low Virulence.