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Outputs (87)

Parasite Population Genetic Contributions to the Schistosomiasis Consortium for Operational Research and Evaluation within Sub-Saharan Africa (2020)
Journal Article
Webster, J. P., Neves, M. I., Webster, B. L., Pennance, T., Rabone, M., Gouvras, A. N., …Rollinson, D. (2020). Parasite Population Genetic Contributions to the Schistosomiasis Consortium for Operational Research and Evaluation within Sub-Saharan Africa. American Journal of Tropical Medicine and Hygiene, https://doi.org/10.4269/ajtmh.19-0827

Analyses of the population genetic structure of schistosomes under the “Schistosomiasis Consortium for Operational Research and Evaluation” (SCORE) contrasting treatment pressure scenarios in Tanzania, Niger, and Zanzibar were performed to provide su... Read More about Parasite Population Genetic Contributions to the Schistosomiasis Consortium for Operational Research and Evaluation within Sub-Saharan Africa.

Multihost Transmission of Schistosoma mansoni in Senegal, 2015–2018 (2020)
Journal Article
Catalano, S., Léger, E., Fall, C. B., Borlase, A., Diop, S. D., Berger, D., …Webster, J. P. (2020). Multihost Transmission of Schistosoma mansoni in Senegal, 2015–2018. Emerging Infectious Disease, 26(6), https://doi.org/10.3201/eid2606.200107

In West Africa, Schistosoma spp. are capable of infecting multiple definitive hosts, a lifecycle feature that may complicate schistosomiasis control. We characterized the evolutionary relationships among multiple Schistosoma mansoni isolates collecte... Read More about Multihost Transmission of Schistosoma mansoni in Senegal, 2015–2018.

Toward Improving Interventions Against Toxoplasmosis by Identifying Routes of Transmission Using Sporozoite- specific Serological Tools (2020)
Journal Article
Walker, M., Webster, J. P., & Milne, G. (2020). Toward Improving Interventions Against Toxoplasmosis by Identifying Routes of Transmission Using Sporozoite- specific Serological Tools. Clinical Infectious Diseases, https://doi.org/10.1093/cid/ciaa428

Background. Horizontal transmission of Toxoplasma gondii occurs primarily via ingestion of environmental oocysts or con- sumption of undercooked/raw meat containing cyst-stage bradyzoites. The relative importance of these 2 transmission routes remain... Read More about Toward Improving Interventions Against Toxoplasmosis by Identifying Routes of Transmission Using Sporozoite- specific Serological Tools.

Divergence across mitochondrial genomes of sympatric members of the Schistosoma indicum group and clues into the evolution of Schistosoma spindale (2020)
Journal Article
Jones, B. P., Norman, B. F., Borrett, H. E., Attwood, S. W., Mondal, M. M. H., Walker, A. J., …Lawton, S. P. (2020). Divergence across mitochondrial genomes of sympatric members of the Schistosoma indicum group and clues into the evolution of Schistosoma spindale. https://doi.org/10.1038/s41598-020-57736-x

Schistosoma spindale and Schistosoma indicum are ruminant-infecting trematodes of the Schistosoma indicum group that are widespread across Southeast Asia. Though neglected, these parasites can cause major pathology and mortality to livestock leading... Read More about Divergence across mitochondrial genomes of sympatric members of the Schistosoma indicum group and clues into the evolution of Schistosoma spindale.

Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda (2019)
Journal Article
Faust, C. L., Crotti, M., Moses, A., Oguttu, D., Wamboko, A., Adriko, M., …Lamberton, P. H. L. (2019). Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda. https://doi.org/10.1186/s13071-019-3860-6

Precision mapping of snail habitat provides a powerful indicator of human schistosomiasis transmission (2019)
Journal Article
Wood, C. L., Sokolow, S. H., Jones, I. J., Chamberlin, A. J., Lafferty, K. D., Kuris, A. M., …De Leo, G. A. (2019). Precision mapping of snail habitat provides a powerful indicator of human schistosomiasis transmission. Proceedings of the National Academy of Sciences, 116(46), 23182-23191. https://doi.org/10.1073/pnas.1903698116

Recently, the World Health Organization recognized that efforts to interrupt schistosomiasis transmission through mass drug administration have been ineffective in some regions; one of their new recommended strategies for global schistosomiasis contr... Read More about Precision mapping of snail habitat provides a powerful indicator of human schistosomiasis transmission.

Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing (2019)
Journal Article
Doyle, S. R., Sankaranarayanan, G., Allan, F., Berger, D., Jimenez Castro, P. D., Collins, J. B., …Holroyd, N. (2019). Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing. Frontiers in Genetics, 10, https://doi.org/10.3389/fgene.2019.00826

Whole-genome sequencing is being rapidly applied to the study of helminth genomes, including de novo genome assembly, population genetics, and diagnostic applications. Although late-stage juvenile and adult parasites typically produce sufficient DNA... Read More about Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing.

Mini-FLOTAC as an alternative, non-invasive diagnostic tool for Schistosoma mansoni and other trematode infections in wildlife reservoirs (2019)
Journal Article
Catalano, S., Symeou, A., Marsh, K. J., Borlase, A., Léger, E., Fall, C. B., …Webster, J. P. (2019). Mini-FLOTAC as an alternative, non-invasive diagnostic tool for Schistosoma mansoni and other trematode infections in wildlife reservoirs. https://doi.org/10.1186/s13071-019-3613-6

Schistosomiasis and food-borne trematodiases are not only of major public health concern, but can also have profound implications for livestock production and wildlife conservation. The zoonotic, multi-host nature of many digenean trematodes is a sig... Read More about Mini-FLOTAC as an alternative, non-invasive diagnostic tool for Schistosoma mansoni and other trematode infections in wildlife reservoirs.