Outputs (52)

Individual Monitoring of Activity and Lameness in Conventional and Slower-Growing Breeds of Broiler Chickens Using Accelerometers (2023)
Journal Article
Pearce, J., Chang, Y. R., & Abeyesinghe, S. (2023). Individual Monitoring of Activity and Lameness in Conventional and Slower-Growing Breeds of Broiler Chickens Using Accelerometers. Animals, 13(9), 1432. https://doi.org/10.3390/ani13091432

Accelerometers are increasingly being investigated to detect animal behaviour as a method for monitoring individual welfare that overcomes manual challenges associated with time, re-source, and discrete sampling. We investigated the effects of broile... Read More about Individual Monitoring of Activity and Lameness in Conventional and Slower-Growing Breeds of Broiler Chickens Using Accelerometers.

Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken (2021)
Journal Article
Abeyesinghe, S., Abeyesinghe, S., Chancellor, N., Hernandez Moore, D., Chang, Y., Pearce, J., …Nicol, C. (2021). Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken. animal, 15(7), https://doi.org/10.1016/j.animal.2021.100261

Broiler chickens are prone to a range of complex health and welfare issues. To support informed selection of welfare traits whilst minimising impact on production efficiency and to address a major gap in understanding, we systematically explored asso... Read More about Associations between behaviour and health outcomes in conventional and slow-growing breeds of broiler chicken.

The Effect of Visitors on the Behavior of Zoo-Housed Western Lowland Gorillas (Gorilla gorilla gorilla) (2020)
Journal Article
Lewis, R. N., Chang, Y. M., Ferguson, A., Lee, T., Clifforde, L., & Abeyesinghe, S. M. (2020). The Effect of Visitors on the Behavior of Zoo-Housed Western Lowland Gorillas (Gorilla gorilla gorilla). Zoo Biology, https://doi.org/10.1002/zoo.21552

Primates, especially apes, are popular with the public, often attracting large crowds. These crowds could cause behavioral change in captive primates, whether positive, neutral, or negative. We examined the impact of visitors on the behavior of six w... Read More about The Effect of Visitors on the Behavior of Zoo-Housed Western Lowland Gorillas (Gorilla gorilla gorilla).

Identification of Production Chain Risk Factors for Slaughterhouse Condemnation of Broiler Chickens’ (2020)
Journal Article
Buzdugan, S. N., Chang, Y. M., Huntington, B., Rushton, J., Guitian, J., Alarcon, P., & Blake, D. P. (2020). Identification of Production Chain Risk Factors for Slaughterhouse Condemnation of Broiler Chickens’. Preventive Veterinary Medicine, 105036. https://doi.org/10.1016/j.prevetmed.2020.105036

Slaughterhouse condemnation of broiler chickens results from identification of polymorphic pathological conditions during meat inspection from arrival and on theslaughter line. While conditions that result in condemnation are multifactorial, identifi... Read More about Identification of Production Chain Risk Factors for Slaughterhouse Condemnation of Broiler Chickens’.

Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation (2020)
Journal Article
Wu, Y., Chang, Y. M., Polton, G., Stell, A. J., Szladovits, B., Macfarlane, M., …Garden, O. A. (2020). Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation. Frontiers in Oncology, 10, https://doi.org/10.3389/fonc.2020.00307

Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs. Two DLBCL subtypes based on cell of origin are generally recognized, germinal center B (GCB)-like and activated B cell (A... Read More about Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation.

Decision tree machine learning applied to bovine tuberculosis risk factors to aid disease control decision making (2019)
Journal Article
Romero, M. P., Chang, Y. M., Brunton, L. A., Parry, J., Prosser, A., Upton, P., …Drewe, J. A. (2019). Decision tree machine learning applied to bovine tuberculosis risk factors to aid disease control decision making. Preventive Veterinary Medicine, https://doi.org/10.1016/j.prevetmed.2019.104860

Identifying and understanding the risk factors for endemic bovine tuberculosis (TB) in cattle herds is critical for the control of this disease. Exploratory machine learning techniques can uncover complex non-linear relationships and interactions wit... Read More about Decision tree machine learning applied to bovine tuberculosis risk factors to aid disease control decision making.

Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice (2019)
Journal Article
Ying Wu, , Chang, Y. M., Stell, A. J., Priestnall, S. L., Sharma, E., Goulart, M. R., …Garden, O. A. (2019). Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice. https://doi.org/10.1038/s41598-019-50065-8

Regulatory T cells (Tregs) are a double-edged regulator of the immune system. Aberrations of Tregs correlate with pathogenesis of inflammatory, autoimmune and neoplastic disorders. Phenotypically and functionally distinct subsets of Tregs have been i... Read More about Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice.

Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows (2019)
Journal Article
Tombacz, K., Peters, L. M., Chang, Y. M., Steele, M., Werling, D., & Gibson, A. J. (2019). Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows. Journal of Dairy Science, 102(10), 9389-9395. https://doi.org/10.3168/jds.2019-16563

In periparturient dairy cows, immune suppression, resulting in decreased neutrophil numbers and function, leads to increased susceptibility to postpartum conditions such as mastitis, retained placenta, and metritis. Administration of polyethylene gly... Read More about Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows.

Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial (2019)
Journal Article
Sanchis-Mora, S., Chang, Y. M., Abeyesinghe, S. M., Fisher, A., Upton, N., Volk, H. A., & Pelligand, L. (2019). Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial. https://doi.org/10.1016/j.tvjl.2019.06.006

Pregabalin is the first-line treatment for neuropathic pain (NeP) in humans. Dogs with Chiari-like malformation and syringomyelia (CM/SM) associated with NeP could benefit from pregabalin. The aim of this study was to evaluate the efficacy of pregaba... Read More about Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial.

Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome (2019)
Journal Article
Pittaway, R., Dobromylskyj, M. J., Erles, K., Pittaway, C. E., Suárez-Bonnet, A., Chang, Y. M., & Priestnall, S. L. (2019). Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome. Veterinary Pathology, 56(6), 868-877. https://doi.org/10.1177/0300985819854435

Nonocular melanocytic neoplasia is considered uncommon in cats yet is routinely encountered in diagnostic pathology and recognized to exhibit a wide variation in biological behavior. Accurate prediction of clinical outcomes is challenging with no wid... Read More about Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome.